Nephrolithiasis Associated with Normocalcemic or Hypercalcemic Primary Hyperparathyroidism: An Update on Medical Management

Abstract

calculi, hypercalciuria, bone loss and fractures [10]. In any case, nephrolithiasis, the aspect that concerns us here, is the most common complication of PHPT, occurring in 15-20% of patients with the hypercalcemic form [11] and even the normocalcemic form seems burdened with a similar high prevalence of nephrolithiasis (18.2% according to Amaral et al.) [12]. Subclinical nephrolithiasis has also been described in patients with the asymptomatic form, and indeed subclinical nephrocalcinosis and nephrolithiasis are

Recurrent Nephrolithiasis Leading to Renal Failure: A Neglected Primary Hyperparathyroidism

“…Primary Hyperparathyroidism (PHPT) is a common condition affecting up to 4 per 1000 individuals, and the majority of cases are due to adenoma or hyperplasia of the gland (6).…”