Nephrological aspects of complement-mediated thrombotic microangiopathy

Смирнов, А В; Karunnaya, A. V.; Добронравов, В. А.

doi:10.17116/terarkh201789634-40

Cited by 3 publications

(1 citation statement)

References 22 publications

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“…In addition, phosphorus helps for the growth, maintenance, and repair of all tissues and cells, and to produce genetic building blocks, DNA and RNA. Phosphorus is also needed to help balance and make proper use of other vitamins and minerals, including vitamin D, iodine, magnesium, and zinc (Noori et al, 2010;Smirnov et al, 2010). However, several studies suggested that higher intakes of phosphorus can be associated with an increased risk of cardiovascular disease.…”

Section: Fortification Of Dried Shrimp and Sesame Seeds And Selectionmentioning

confidence: 99%

Quality of Thai Furikake dried seasoning powder fortified with natural calcium and phosphorus

Siripongvutikorn,

Banphot,

Rampoei

et al. 2023

Ital. J. Food Sci.

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Fresh Liang leaves, a local vegetable of Southern Thailand, were dried, seasoned, and fortified with different ratios of dried shrimp and sesame seeds at 1%–5% for making a rice topping product (Furikake) named as F1-F5. The F5 obtained the highest consumer acceptability with high calcium and phosphorus contents at 4,299.45 mg/kg and 3,436.32 mg/kg, respectively. Total phenolic content and DPPH radical scavenging antioxidant activity of F5 were 2,575.22 µg GAE/g DW and 676.99 µg TE/g DW, respectively. Total chlorophyll and carotenoid contents were 11.38 mg/g DW and 3.52 mg/g DW, respectively. An increment of aw and moisture content (p < 0.05) of the F5 kept at higher temperature storage was noticed, and a reduction of L* value under all storage conditions was noticed.

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Section: Fortification Of Dried Shrimp and Sesame Seeds And Selectionmentioning

confidence: 99%

Quality of Thai Furikake dried seasoning powder fortified with natural calcium and phosphorus

Siripongvutikorn,

Banphot,

Rampoei

et al. 2023

Ital. J. Food Sci.

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Infrared Non‐Invasive Exhaled Biomarker Sensing: A Review

Ranu,

Rahman

et al. 2023

Advanced Sensor Research

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Exhaled breath analysis is considered an effective tool for diagnosing the patient's metabolic status because of its non‐invasive nature. Gas chromatography‐mass spectrometry (GC‐MS) and other mass spectrometry techniques are widely used for exhaled breath analysis. Nevertheless, the requirement of a handheld device for real‐time analysis and rapid processing time of multiple samples leads to advancing infrared (IR) based breath gas sensing techniques. Herein, the IR gas sensing technologies are discussed with a focus on non‐dispersive infrared (NDIR), photoacoustic (PAS), and tunable diode laser absorption spectroscopy (TDLAS) gas sensing technologies because of their highly selective gas detection among compound gases (mixture of VOCs), as well as their corresponding sensing mechanisms and characteristics, for real‐time monitoring of exhaled biomarkers. Carbon dioxide, acetone, ammonia, nitric oxide, methane, and ethylene are the significant biomarkers elaborated in this work with their respective clinical applications and the significance of non‐invasive real‐time monitoring using IR detectors. Challenges in selectivity and clinical trials leads to focus on this review. Current market analysis, present status of different techniques to detect specific biomarkers and other challenges with their possible solutions discussed in this review aid in developing highly selective IR‐based handheld breath VOC analyzers for early diagnosis and screening.

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Atypical hemolytic-uremic syndrome and glomerulopathies. Clinical observation and a brief literature review

Kozlovskaya

Korotchaeva

Demyanova

2020

Nefrologiâ (St.-Peterbg.)

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According to modern concepts, for the development of atypical hemolytic uremic syndrome (aHUS) in predisposed individuals, additional factors are necessary, which today are considered as complement-activating states. The most common of them are infections, pregnancy and childbirth, autoimmune diseases, transplantation of bone marrow and solid organs, some medications. Less commonly, aHUS is preceded by malignant arterial hypertension and glomerular kidney disease. Clinical observation of a patient suffering from a steroid-sensitive relapsing nephrotic syndrome (NS) for 10 years, in which after a viral infection first increased blood pressure, developed impaired renal function and hematological manifestations of thrombotic microangiopathy (ТМА), is given. In the presented observation, aHUS developed as a “second disease” in a patient with previously diagnosed glomerular kidney disease, which led to the rapid progression of chronic kidney disease with the development of terminal renal failure. This is evidenced by the nature of the course of the disease – NS recurring after acute respiratory viral infections, not accompanied by changes in urine sediment, arterial hypertension, impaired renal function and easily stopped by corticosteroids with rapid disappearance of proteinuria and normalization of protein blood counts. The change in the clinical picture of nephritis after a herpes zoster infection made us think about the development of a second renal disease of a different nature, other than glomerulonephritis. Undoubted AKI, combined with severe anemia and thrombocytopenia, was the basis for the exclusion of primarily TMA. The exclusion of TTP, STEC-HUS and the most common causes of secondary TMA made it possible to diagnose atypical HUS. The role of NS in the development of TMA is discussed. Blood coagulation disorders and VEGF-dependent mechanisms are considered as possible mechanisms.

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Nephrological aspects of complement-mediated thrombotic microangiopathy

Abstract: Analysis of this series of cases confirms the idea about the severity of TMA due to multiple organ dysfunction and the high risk of end-stage renal failure at late diagnosis. The key points of better renal prognosis are the earliest detection and treatment of the disease.

Cited by 3 publications

References 22 publications

Quality of Thai Furikake dried seasoning powder fortified with natural calcium and phosphorus

Quality of Thai Furikake dried seasoning powder fortified with natural calcium and phosphorus

Infrared Non‐Invasive Exhaled Biomarker Sensing: A Review

Atypical hemolytic-uremic syndrome and glomerulopathies. Clinical observation and a brief literature review

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