Nephrotic syndrome following a single bee sting in a child

Abstract

The occurrence of nephrotic syndrome following a bee sting is rarely reported in the literature. Hypersensitivity is believed to be the precipitating factor for the renal disease. We report a two-year-old boy, who developed generalized edema and decreased urine output, seven days after a bee sting. Physical examination and laboratory findings were consistent with nephrotic syndrome; and corticosteroid treatment induced prompt remission with resolution of clinical symptoms and normalization of laboratory findings. There was no relapse of the disease during a one-year follow up.

Acute renal failure and/or rhabdomyolysis due to multiple bee stings: A retrospective study

“…Recently, a case of nephritic syndrome induced by single bee sting in a child was reported. [27] Bee-sting is also reported to cause cavernous sinus thrombosis. [28] Death resulted from bee sting is uncommon.…”

Nephritic syndrome following multiple bee stings: a late hypersensitivity reaction

“…Insect stinginduced acute interstitial nephritis and nephrotic syndrome have shown improvement following use of corticosteroids. 7,8,10,11 Although an immunological mechanism is thought to have played a significant role in the pathogenesis of renal involvement in this patient, corticosteroids were not used because of the clinical improvement.…”

“…9 Bee sting has been reported to also cause the nephrotic syndrome. 10,11 Initial management should be removal of the barbed stings within 10-20 seconds by flicking or scraping off, which may prevent injection of additional venom. 12 Local reaction to bee sting is generally transient and does not require medical Nag et al Nephritic syndrome after bee stings treatment.…”

Acute Kidney Injury Due to Acute Cortical Necrosis Following a Single Wasp Sting

“…[18][19][20][21] In addition to AKI, wasp or bee stings have also been associated with reports of nephrotic syndrome and type 1 renal tubular acidosis. [22][23][24][25][26] Our patient had a single wasp sting on her hand and went on to develop AKI without any evidence of hypotension, severe allergic manifestations, hemolysis, or rhabdomyolysis. As the recovery of renal function was delayed and the cause of renal failure was unclear, a renal biopsy was done.…”