Nephrotoxic Effects of Mercury Exposure and Smoking Among Egyptian Workers in a Fluorescent Lamp Factory

El-Safty, Ibrahim; Shouman, Ahmed; Amin, Nour El-Din

doi:10.1016/s0188-4409(02)00462-9

Cited by 18 publications

(11 citation statements)

References 24 publications

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“…In 2016–2017 CHMS (20–39 yr: 0.55, 40–59 yr: 0.85, 60–79 yr: 0.83 μg/L), Hg concentration increased with increasing age up to ≤59 yr, but decreased again at ≥60 yr, showing a similar trend despite slight differences [ 7 ]. Similar to the present study, correlations of the concentration level with smoking [ 25 , 26 , 27 , 28 ] and drinking [ 27 , 29 , 30 ] status have been identified in some studies. Correlations with household income and education level have been similarly identified [ 27 , 31 , 32 ].…”

Section: Discussionsupporting

confidence: 89%

Assessment of Lead and Mercury Exposure Levels in the General Population of Korea Using Integrated National Biomonitoring Data

Seo

Hong

Kim

2021

IJERPH

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In Korea, the estimated values of blood lead (Pb) and mercury (Hg) levels differ between two national-level biomonitors, namely the Korean National Environmental Health Survey and the Korea National Health and Nutrition Examination Survey. The present study used integrated data from these surveys to estimate the representative values of the change in concentration and recent distribution characteristics. The yearly trend of age-standardized exposure levels in regular adults was identified, and the geometric mean (GM) adjusted according to demographic characteristics was presented. Age-standardized GM for blood Pb and Hg in the integrated data was 2.06 and 3.64 μg/L in 2008, respectively, which decreased to 1.55 and 2.92 μg/L, respectively, by 2017. Adjusted GMs from most recently conducted surveys (2015–2017) were 1.61 and 2.98 μg/L for blood Pb and Hg, respectively. In particular, the adjusted percentage of blood Hg exceeding the reference value of 5 μg/L was 20.79%. While the blood Pb and Hg exposure levels are decreasing in Korea, the levels remain high relative to those in other countries. The Hg levels exceeded the reference value in many individuals. Therefore, continued biomonitoring must be conducted, and a reduction plan and exposure management are needed for harmful metals, including Hg.

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Section: Discussionsupporting

confidence: 89%

Assessment of Lead and Mercury Exposure Levels in the General Population of Korea Using Integrated National Biomonitoring Data

Seo

Hong

Kim

2021

IJERPH

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“…Cigarette smokers are exposed to significant amounts of cadmium (Cd) and lead (Pb) (54), which accumulate in kidney tissue more than in any other organ and are toxic at very low dosages (55). According to studies from Egypt, smoking has toxic effects on tubular cells, which are synergistic to occupational Pb (56), mercury (57), and silica (58) exposure. Dietary Cd and Pb seems to confer mild tubular dysfunction, whereas dietary exposure plus cigarette smoking is associated with tubular plus glomerular dysfunction (59).…”

Section: Nonhemodynamic Mechanisms As Potential Mediators Of Smoking-mentioning

confidence: 99%

Smoking

Orth

Hallan²

2008

Clinical Journal of the American Society of Nephrology

256

174

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Although it is beyond any doubt that smoking is the number one preventable cause of death in most countries, smoking as an independent progression factor in renal disease has been questioned against the background of evidence-based criteria. This is because information from large, randomized, prospective studies that investigate the effects of smoking on renal function in healthy individuals as well as in patients with primary or secondary renal disease are lacking. Since 2003, a substantial number of clinical and experimental data concerning the adverse renal effects of smoking have been published, including large, prospective, population-based, observational studies. These more recent data together with evidence from experimental studies clearly indicate that smoking is a relevant risk factor, conferring a substantial increase in risk for renal function deterioration. This review summarizes the present knowledge about the renal risks of smoking as well as the increased cardiovascular risk caused by smoking in patients with chronic kidney disease. The conclusion is that smoking is an important renal risk factor, and nephrologists have to invest more efforts to motivate patients to stop smoking.

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“…The kidneys are one of the main target organs for elemental mercury, which accumulates in the kidneys, some studies have shown this effects (El-Safty et al, 2003;Franko et al, 2005). However, in occupational field, the long-term effects of elemental Hg on the kidneys have not been studied in detail.…”

Section: U-hgmentioning

confidence: 99%

Impact of occupational exposure to elemental mercury on some antioxidative enzymes among dental staff

Samir

Aref

2011

Toxicol Ind Health

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Nephrotoxic Effects of Mercury Exposure and Smoking Among Egyptian Workers in a Fluorescent Lamp Factory

Cited by 18 publications

References 24 publications

Assessment of Lead and Mercury Exposure Levels in the General Population of Korea Using Integrated National Biomonitoring Data

Assessment of Lead and Mercury Exposure Levels in the General Population of Korea Using Integrated National Biomonitoring Data

Smoking

Impact of occupational exposure to elemental mercury on some antioxidative enzymes among dental staff

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