Nerve biopsy in Indian patients with mononeuropathy multiplex of undetermined etiology

Nerve biopsy is still the gold standard for the diagnosis of peripheral nerve vasculitis. In other indications, sural or superficial peroneal nerve biopsies are less frequently done, because less invasive methods have become available. Modern imaging methods allow localization of nerve damage, such that targeted fascicular biopsies can be done. Immunofluorescence staining of teased nerve fibers has contributed to the understanding of the pathophysiology of inflammatory neuropathies. Skin biopsy has become a routine method to diagnose small fiber neuropathy.

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Nerve biopsy in Indian patients with mononeuropathy multiplex of undetermined etiology

Abstract: In 43 of 68 Indian patients (63%) with MM, nerve biopsy identified a definite (26 patients) or probable (17 patients) etiology. Nerve biopsy is a valuable investigation in MM that frequently results in a diagnosis of leprosy in India. Muscle Nerve, 2016 Muscle Nerve 55: 23-27, 2017.

Cited by 4 publications

References 23 publications

Sural nerve biopsy in peripheral neuropathies: 30-year experience from a single center

Sural nerve biopsy in peripheral neuropathies: 30-year experience from a single center

Evaluation of polymerase chain reaction in nerve biopsy specimens of patients with Hansen's disease

Nerve and skin biopsy in neuropathies

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