Nerve Sparing, Robot-Assisted Radical Cystectomy with Intracorporeal Bladder Substitution in the Male

Asimakopoulos, Anastasios D.; Campagna, Adriano; Gakis, Georgios; Corona-Montes, Víctor Enrique; Piéchaud, Thierry; Hoepffner, Jean-Luc; Mugnier, Camille; Gaston, R.

doi:10.1016/j.juro.2016.04.114

Cited by 53 publications

(51 citation statements)

References 28 publications

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“…showed that 74% and 88% of patients achieved daytime continence (1 pad per day) for 6 and 12 months, respectively, whereas Asimakopoulos et al . showed that 75% and 100% of patients experienced daytime continence (0 pad per day) for 1 and 12 months, respectively . Recently, Kouk et al .…”

Section: Introductionmentioning

confidence: 99%

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Current status and future perspective of robot‐assisted radical cystectomy for invasive bladder cancer

Fujimura

2019

Int J of Urology

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The current status of robot‐assisted radical cystectomy was reviewed 16 years after the initial robot‐assisted radical cystectomy for the treatment of invasive bladder cancer. Articles associated with robot‐assisted radical cystectomy and written in English were selected from the PubMed database from January 2003 to February 2019. The present review article focused on the distribution of robot‐assisted radical cystectomy, patient selection, preoperative management, surgical technique, lymph node dissection, urinary diversion, recurrence pattern, oncological outcomes, cost, learning curve, complications and educational programs. A total of 400 articles were divided according to the country of the first author's affiliation. The USA was the most dominant at 198 (50%), whereas the number of articles from the countries belonging to the Urological Association of Asia was 15 (3.8%) for China, 17 (4.3%) for South Korea, 10 (2.5%) for Japan, eight (2%) for Taiwan, eight (2%) for Turkey and one (0.2%) for Iran. The percentage of robot‐assisted radical cystectomy carried out is increasing, and intracorporeal urinary diversion and ileal neobladder are also frequently carried out. With a refined technique being performed in high‐volume centers, robot‐assisted radical cystectomy has contributed to the reduction in transfusion rate, length of stay and severe complications; however, it has not yet shown any cancer‐specific survival benefits. Robot‐assisted radical cystectomy is not fully spread throughout the Urological Association of Asia. Further investigation with respect to worldwide results is needed to prove the real benefit of robot‐assisted radical cystectomy regarding low morbidity, reduced total medical cost, and survival benefit. In the era of precision medicine, appropriate drug and surgery will be given based on each genetic profile.

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Section: Introductionmentioning

confidence: 99%

“…and Asimakopoulos et al . reported that 45% and 77.5% of patients, respectively, who received nerve‐sparing RARC achieved potency . Tyritzis et al .…”

Section: Introductionmentioning

confidence: 99%

Current status and future perspective of robot‐assisted radical cystectomy for invasive bladder cancer

Fujimura

2019

Int J of Urology

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“…The pelvic autonomic nerves, specifically the sympathetic fibres, are known to control urethral tonus at rest and assure urinary continence . A beneficial impact of nerve sparing (NS) on urinary continence after urinary diversion with an OBS has been reported in a few open and robot‐assisted RC series with short to mid‐term follow‐up . However, the debate is ongoing as to whether NS affects long‐term outcomes because it is unknown whether the positive impact of NS persists over time.…”

Section: Introductionmentioning

confidence: 99%

Nerve‐sparing radical cystectomy has a beneficial impact on urinary continence after orthotopic bladder substitution, which becomes even more apparent over time

et al. 2018

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“…RCTs with sufficient power are awaited. Table shows the available RARC studies of neobladders with published functional outcomes …”

Section: Functional Outcomesmentioning

confidence: 99%

Is the open cystectomy era over? An update on the available evidence

Tyritzis

Wiklund

2017

Int J of Urology

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In 2018, robot-assisted radical cystectomy will enter its 15th year. In an era where an effort is being made to standardize complication reporting and videos of the procedure are readily available, it is inevitable and justified that like everything novel, robot-assisted radical cystectomy should be scrutinized against the gold standard, open radical cystectomy. The present comparison is focused on several parameters: oncological, functional and complication outcomes, and direct and indirect costs. Metaanalysis and prospective randomized trials comparing robot-assisted radical cystectomy versus open radical cystectomy have been published, showing an oncological equivalence and in some cases an advantage of robot-assisted radical cystectomy in terms of postoperative morbidity. In the present review, we attempt to update the available knowledge on this debate and discuss the limitations of the current evidence that prevent us from drawing safe conclusions.

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Nerve Sparing, Robot-Assisted Radical Cystectomy with Intracorporeal Bladder Substitution in the Male

Cited by 53 publications

References 28 publications

Current status and future perspective of robot‐assisted radical cystectomy for invasive bladder cancer

Current status and future perspective of robot‐assisted radical cystectomy for invasive bladder cancer

Nerve‐sparing radical cystectomy has a beneficial impact on urinary continence after orthotopic bladder substitution, which becomes even more apparent over time

Is the open cystectomy era over? An update on the available evidence

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