Nervous System

Caplan, Elaine R.

doi:10.1002/9781118729038.ch15

Cited by 4 publications

(8 citation statements)

References 77 publications

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“…No metastasis was observed in the present case, which is consistent with the literature, since less than 20% of the cases metastasize (CAPLAN, 2012). Nevertheless, despite the high rate of recurrence reported for this type of tumor (CAPLAN, 2012;HIGGINS et al, 2017), it was not observed in the present case.…”

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)supporting

confidence: 92%

“…The one-year evolution time reported in the present case is longer than in other cases in the literature for canine MPNST, which reported evolution times lower than six months (ANDREW, 1999;BARATT et al, 2015;GIBSON et al, 2016). No metastasis was observed in the present case, which is consistent with the literature, since less than 20% of the cases metastasize (CAPLAN, 2012). Nevertheless, despite the high rate of recurrence reported for this type of tumor (CAPLAN, 2012;HIGGINS et al, 2017), it was not observed in the present case.…”

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)supporting

confidence: 90%

“…is rare in dog, with few reports in veterinary medicine literature (SIRRI et al, 2016;HIGGINS et al, 2017) and incidence reported of 0.5% to 2.0% of all skin tumors (CAPLAN, 2012). Peripheral nerve sheath tumors (PNST) are a group of mesenchymal neoplasms, and the term schwannoma is used when the tumor cells are exclusively of Schwann-cell origin.…”

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)mentioning

confidence: 99%

“…The treatment for MPNST is surgical (CAPLAN, 2012). The removal of the tumor and its surrounding tissues may be vital for the patient's survival (PARK et al, 2011;TAVASOLY et al, 2013).…”

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)mentioning

confidence: 99%

“…MPNST include malignant schwannoma and malignant neurofibroma (or neurofibrosarcoma) (CAPLAN, 2012;PEKMEZCI et al, 2015). In human medicine, this distinction can be made by immunohistochemical analysis with S100, GFAP, or other specific neural markers (CUNHA et al, 2012;LIU et al, 2013;ANITHAKUMARI et al, 2015).…”

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)mentioning

confidence: 99%

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Case report and immunohistochemical study of a malignant peripheral nerve sheath tumor in a dog

Moreira

Borges

Serra

et al. 2017

Braz. J. Vet. Res. Anim. Sci.

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Malignant peripheral nerve sheath tumor is rare and rarely reported in dogs. The term neurofibroma/sarcoma is classically used when the tumor is composed of Schawann and perineural cells. This work describes the clinical, histopathological, and immunohistochemical case of a subcutaneous malignant peripheral nerve sheath tumor, most likely a malignant neurofibroma located in the pelvic member of a Rottweiler dog. Histopathological features and immunohistochemical analysis corroborated the diagnosis, showing positivity for S-100 protein, vimentin, and CD57, and was useful to distinguish this type of neoplasm from other malignancies of similar morphologies. ResumoO tumor maligno da bainha do nervo periférico é raro e pouco descrito em cães. Classicamente, o termo "neurofibroma/ sarcoma" é empregado quando o tumor é composto por células de Schwann e células perineurais. Neste relato são descritos os achados clínicos, histopatológicos e imuno-histoquímicos de um caso de tumor maligno da bainha do nervo periférico, provavelmente neurofibrossarcoma, localizado no subcutâneo do membro pélvico de um cão da raça Rottweiler. Os achados histopatológicos associados às observações imuno-histoquímicas contribuíram para o diagnóstico, sendo observada positividade para proteína S-100, vimentina e CD57, permitindo a diferenciação da neoplasia em questão de outros tumores malignos com características morfológicas similares. Palavras-chave: Neoplasia. Membro pélvico. Canino. Marcadores.

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Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)supporting

confidence: 92%

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)supporting

confidence: 90%

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)mentioning

confidence: 99%

“…The treatment for MPNST is surgical (CAPLAN, 2012). The removal of the tumor and its surrounding tissues may be vital for the patient's survival (PARK et al, 2011;TAVASOLY et al, 2013).…”

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)mentioning

confidence: 99%

Section: Malignant Peripheral Nerve Sheath Tumor (Mpnst)mentioning

confidence: 99%

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Case report and immunohistochemical study of a malignant peripheral nerve sheath tumor in a dog

Moreira

Borges

Serra

et al. 2017

Braz. J. Vet. Res. Anim. Sci.

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Neurofibroma of the ulnar nerve in the carpal canal in a dog: treatment by marginal neurectomy

Basa

Crowley²,

Johnson

2018

J of Small Animal Practice

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Peripheral nerve sheath tumours arising in the plexus or peripheral nerves can be treated by limb amputation. There are few reports of these tumours affecting peripheral nerves in the distal regions of the limbs. Here we describe a case of neurofibroma affecting the palmar branch of the ulnar nerve in an Irish setter. Surgical treatment in the region of the carpus by ulnar neurectomy resulted in resolution of chronic thoracic limb lameness. At 11 months following the surgery, clinical examination and MRI did not detect any evidence of recurrence. Neurectomy may be a feasible option for management of selected cases of distally located peripheral nerve sheath tumours.

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Schwannoma Maligno Em Face De Cão - Relato De Caso

Tournier

Correa

Minto

et al. 2021

Ars Vet

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O Schwannoma trata-se de um tipo de tumor maligno da bainha dos nervos periféricos (TMBNP) incomum em pequenos animais. Não há predileção por raça e são mais comumente diagnosticados em cães de meia idade a idosos, podendo acometer diferentes regiões do corpo, entretanto, há raros relatos de acometimento em face. O presente trabalho tem por objetivo relatar um caso de TMBNP em face de um cão, macho, SRD, de 14 anos. O paciente apresentava uma formação de aproximadamente 10 cm em região facial esquerda, acometendo maxila e arco zigomático, com comprometimento também de seu globo ocular. Considerou-se a remoção cirúrgica paliativa devido a extensão da formação e seu posterior diagnóstico se deu através do exame histopatológico. Após a evolução clínica desfavorável que o paciente apresentou após o procedimento cirúrgico e devido ao prognóstico desfavorável frente ao diagnóstico de TMBNP, optou-se então pela eutanásia do paciente.

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Nervous System

Cited by 4 publications

References 77 publications

Case report and immunohistochemical study of a malignant peripheral nerve sheath tumor in a dog

Case report and immunohistochemical study of a malignant peripheral nerve sheath tumor in a dog

Neurofibroma of the ulnar nerve in the carpal canal in a dog: treatment by marginal neurectomy

Schwannoma Maligno Em Face De Cão - Relato De Caso

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