Netherton's syndrome

Abstract

History. After an uncomplicated pregnancy the boy was born as the first child of healthy Turkish consanguineous parents. Immediately after birth a red and scaly skin was noted. By 2 months the child was transferred to the Sophia Children's Hospital (SCH). Examination. At birth a red skin was noted with peeling on the chin, arms and hands. He did not have the appearance of a collodion baby. One week after birth there was gross lamellar scaling. At the age of 2 months the skin was yellow without any subcutaneous fat. There were fissures but no bullae. The nails were normal and the hair was sparse. There were 'dermogenetic' contractures.