Background:Spontaneous pneumomediastinum (SPM) is an uncommon disorder. It is rarely
reported in paediatric patients and may be accompanied by subcutaneous
emphysema. It is usually benign and self-limiting, with only supportive
therapy being needed, but severe cases may require invasive measures. Asthma
exacerbations have classically been described as a cause of SPM. However,
detailed descriptions in asthmatic children are scarce. We aimed at
improving the current understanding of the features of SPM and subcutaneous
emphysema, and outcomes, by means of a case report and a systematic
review.Methods:For the systematic review a literature search was performed in PubMed to
identify reported cases of SPM in asthmatic children.Results:The case a 10-year-old asthmatic girl with SPM is reported. The patient
received an inhaled corticosteroid and long-acting beta2 agonist, in
addition to sublingual immunotherapy (SLIT) with eventual control of asthma
symptoms. Review: A total of 114 published cases were found since 1995, most
of them in teenagers; no sex differences were observed. Clinical
presentation was associated with an asthma exacerbation in a number of
cases. Other presenting features were chest pain, dyspnoea, cough, and
particularly acute swelling of the face, neck, and upper chest. Subcutaneous
emphysema was present in most patients. Overall, three cases of pneumothorax
and two cases of pneumorrhachis were reported. Therapy was mainly based on
supportive care, rest, oxygen therapy, analgesics, steroids, and
bronchodilators. All patients recovered spontaneously, in spite of a small
initial increase in SPM in a few cases.Conclusions:Early identification of patients at risk of SPM would avoid the high number
of under-diagnosed cases. Patients should be treated not only with
supportive therapy but also with measures to achieve control of the
underlying cause (such as poorly controlled asthma).