2021
DOI: 10.1101/2021.12.16.472826
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Neural signature of everyday function in older adults at-risk of cognitive impairment

Abstract: Assessment of everyday activities are central to the diagnosis of pre-dementia and dementia. Yet, little is known about the brain substrates and processes that contribute to everyday functional impairment, particularly during early stages of cognitive decline. We investigated everyday function using a complex gait task in normal older adults stratified by risk of cognitive impairment. We applied a novel EEG approach, which combines electroencephalographic with 3D-body tracking technology to measure brain-gait … Show more

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Cited by 3 publications
(2 citation statements)
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“…Figure 5 shows the basic steps to identify or correct artifacts and model spatially resolved brain dynamics tied to the gait cycle that we apply in our proposal. We have validated and applied this analysis pipeline in prior work [ 12 , 15 , 61 ]. Independent component (IC) analysis will be used to parse electroencephalographic signals into ICs.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Figure 5 shows the basic steps to identify or correct artifacts and model spatially resolved brain dynamics tied to the gait cycle that we apply in our proposal. We have validated and applied this analysis pipeline in prior work [ 12 , 15 , 61 ]. Independent component (IC) analysis will be used to parse electroencephalographic signals into ICs.…”
Section: Resultsmentioning
confidence: 99%
“…Figure 3 shows an individual performing the visual-perturbed walking task. The participant walking on a treadmill wearing an electroencephalographic cap is immersed into a large-scale visual flow field designed to destabilize posture [ 61 ]. We superimpose sideway shifts onto a display of dots radiating outward from a central point of extension to create visual perturbations.…”
Section: Methodsmentioning
confidence: 99%