2006
DOI: 10.1016/j.expneurol.2006.02.055
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Neural stem cells for cell replacement therapy for Huntington's disease

Abstract: The research reported in this thesis focused on the potential o f neural precursor cells to provide a suitable source o f neurones which can be used in cell replacement strategies for Huntington's disease. Specifically, the parameters affecting the differentiation o f these cells into neuronal phenotypes were addressed and increasing the survival o f proliferating and differentiating neurones was attempted. In vivo characteristics and the fibre projections o f primary and 10 day expanded ENPs was also assessed… Show more

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References 340 publications
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