Neuralgische Schulteramyotrophie, Klinik und Verlauf

Huffmann, G

doi:10.1007/bf00316145

Cited by 2 publications

(2 citation statements)

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“…For example, some authors found that 36% of patients recover within one year, 75% within two years, and 89% within three years [ 48 ]. Other studies report that only 11 of 83 PTS patients had complete recovery over a 17-year follow-up [ 59 ]. Nonetheless, the likelihood of recovery for each unique lesion should be determined using the basic rules of reinnervation [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Parsonage-Turner Syndrome Following SARS-CoV-2 Infection: A Systematic Review

Cornea

Lata²,

Simu

et al. 2023

Biomedicines

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Parsonage-Turner syndrome (PTS) is an inflammatory disorder of the brachial plexus. Hypothesized underlying causes focus on immune-mediated processes, as more than half of patients present some antecedent event or possible predisposing condition, such as infection, vaccination, exercise, or surgery. Recently, PTS was reported following the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We aimed to investigate data on PTS triggered by SARS-CoV-2 infection to provide an extensive perspective on this pathology and to reveal what other, more specific, research questions can be further addressed. In addition, we aimed to highlight research gaps requiring further attention. We systematically reviewed two databases (LitCOVID and the World Health Organization database on COVID-19) to January 2023. We found 26 cases of PTS in patients with previous SARS-CoV-2 infection. The clinical and paraclinical spectrum was heterogeneous, ranging from classical PTS to pure sensory neuropathy, extended neuropathy, spinal accessory nerve involvement, and diaphragmatic palsy. Also, two familial cases were reported. Among them, 93.8% of patients had severe pain, 80.8% were reported to present a motor deficit, and 53.8% of patients presented muscle wasting. Paresthesia was noted in 46.2% of PTS individuals and a sensory loss was reported in 34.6% of patients. The present systematic review highlights the necessity of having a high index of suspicion of PTS in patients with previous SARS-CoV-2 infection, as the clinical manifestations can be variable. Also, there is a need for a standardized approach to investigation and reporting on PTS. Future studies should aim for a comprehensive assessment of patients. Factors including the baseline characteristics of the patients, evolution, and treatments should be consistently assessed across studies. In addition, a thorough differential diagnosis should be employed.

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Section: Discussionmentioning

confidence: 99%

Parsonage-Turner Syndrome Following SARS-CoV-2 Infection: A Systematic Review

Cornea

Lata²,

Simu

et al. 2023

Biomedicines

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“…There are several reports, however, of less favourable outcomes 50-52. A retrospective evaluation of 44 patients 1 to 7 years after the illness onset showed that 32 still had objective deficits and 17 experiencing intermittent complaints of radicular origins, particularly in patients with jobs of a manual nature 53. Recovery can begin very late in the illness, sometimes up to 6 months 54.…”

Section: Discussionmentioning

confidence: 99%

Motor root conduction in neuralgic amyotrophy: evidence of proximal conduction block

Mills

1999

Journal of Neurology, Neurosurgery & Psychiatry

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Objective-To determine the presence and role of proximal conduction block in neuralgic amyotrophy. Methods-Percutaneous electrical stimulation of cervical roots and brachial plexus was employed in eight patients with neuralgic amyotrophy. Root to Erb's point compound muscle action potential amplitude ratios for abductor digiti minimi, extensor digitorum communis, biceps, and deltoid muscles were compared with results obtained from 10 healthy controls. Results-Conduction block in the nerve to one muscle was found in three of eight patients (38%) suggesting focal proximal demyelination. Repeat studies showed axonal degeneration, resolution, and persistence of conduction block in these three patients respectively. Conclusion-Focal conduction block plays a significant part in the pathogenesis of neuralgic amyotrophy, which is generally regarded as an axon loss process. Therapeutic intervention should be directed to patients with persistent conduction block, with the aim of eradicating the block and possibly minimising subsequent axon loss. (J Neurol Neurosurg Psychiatry 1999;66:586-590)

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Neuralgische Schulteramyotrophie, Klinik und Verlauf

Cited by 2 publications

References 1 publication

Parsonage-Turner Syndrome Following SARS-CoV-2 Infection: A Systematic Review

Parsonage-Turner Syndrome Following SARS-CoV-2 Infection: A Systematic Review

Motor root conduction in neuralgic amyotrophy: evidence of proximal conduction block

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