Neurobehavioral changes in freshwater fishChanna punctatus exposed to fenitrothion

Ram, Murali Dhar; Gopal, Krishna

doi:10.1007/bf01702210

“…Contrasting results have also reported that NE and dopamine concentrations in different brain regions seem to be dependent on the concentration and the duration of exposure to OP and organochlorine insecticides [28,29]. Thus, in contrast with the clear inhibitory effect of these pesticides on brain AChE activity [3,7], available data in fish show that exposure to CB and OP can produce contrasting effects on the levels of brain catecholamines [12,28]. In a recent study concerning effects of short-term (6,12,24,48 h) exposures to carbofuran on AChE activity in goldfish [3], a significant inhibition of brain AChE was found from a 6-h exposure to 50 g/L.…”

Section: Discussionmentioning

confidence: 76%

“…These authors found an increase in dopamine and NE levels in the hypothalamus and cortex after a 15-d exposure to carbaryl, a CB insecticide. Contrasting results have also reported that NE and dopamine concentrations in different brain regions seem to be dependent on the concentration and the duration of exposure to OP and organochlorine insecticides [28,29]. Thus, in contrast with the clear inhibitory effect of these pesticides on brain AChE activity [3,7], available data in fish show that exposure to CB and OP can produce contrasting effects on the levels of brain catecholamines [12,28].…”

Section: Discussionmentioning

confidence: 99%

Biochemical and Behavioral Effects of Carbofuran in Goldfish (Carassius Auratus)

Bretaud¹,

Saglio²,

Saligaut³

et al. 2002

Environ Toxicol Chem

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The effects of concentration (5, 50, and 500 microg/L) and duration (24, 48 h) of exposure to carbofuran, a carbamate insecticide, were assessed on brain catecholamine (norepinephrine [NE] and dopamine), plasma glucose, and hepatic glycogen contents and behavioral activities of goldfish (Carassius auratus). After 24 h of exposure to 50 and 500 microg/L, the level of NE was increased in the olfactory bulbs. The same effect was observed after a 48-h exposure to 500 and 50 microg/L in the telencephalic hemispheres and in the hypothalamus, respectively. An increase in the level of dopamine was also found in hypothalamus after 48 h of exposure to 500 microg/L carbofuran. Plasma glucose increased in concentration after both periods of exposure to carbofuran at 50 and 500 microg/L. Hepatic glycogen concentration decreased after a 48-h exposure to the highest concentration. Behavioral endpoints related to swimming pattern and social interactions were affected after a 24-h exposure to the lowest concentration tested (5 microg/L). The relative sensitivities of these different types of responses to exposure to carbofuran are discussed in light of data on the neurotoxic effects of carbamate and organophosphate insecticides in fish.

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“…Respiratory failure was the syndrome; and inhibition of acetylcholinesterase activity persisted even for 30 days from poisoning. Insecticide Ram et al [ 220 ]: Neurobehavioral changes in freshwater fish exposed 82 Fenoxycarb Insecticide Lenkic et al [ 221 ]: allatostatin may be one of the effectors in the brain by which the pesticides inhibits juvenile hormone biosynthesis.in cockroach. 83 Finasteride Pharmaceutical Fertig et al [ 222 ]: permanent sexual dysfunction and mood changes (fatigue, anxiety, depression and suicidal ideation) during treatment with this 5-alpha-reductase inhibitor.…”

Section: Resultsmentioning

confidence: 99%

Endocrine disruptors also function as nervous disruptors and can be renamed endocrine and nervous disruptors (ENDs)

Séralini

¹

,

Jungers

²

2021

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show abstract

“…Contrasting results have also reported that NE and dopamine concentrations in different brain regions seem to be dependent on the concentration and the duration of exposure to OP and organochlorine insecticides [28, 29]. Thus, in contrast with the clear inhibitory effect of these pesticides on brain AChE activity [3, 7], available data in fish show that exposure to CB and OP can produce contrasting effects on the levels of brain catecholamines [12, 28]. In a recent study concerning effects of short‐term (6, 12, 24, 48 h) exposures to carbofuran on AChE activity in goldfish [3], a significant inhibition of brain AChE was found from a 6‐h exposure to 50 μg/L.…”

Section: Discussionmentioning

confidence: 96%

“…These authors found an increase in dopamine and NE levels in the hypothalamus and cortex after a 15‐d exposure to carbaryl, a CB insecticide. Contrasting results have also reported that NE and dopamine concentrations in different brain regions seem to be dependent on the concentration and the duration of exposure to OP and organochlorine insecticides [28, 29]. Thus, in contrast with the clear inhibitory effect of these pesticides on brain AChE activity [3, 7], available data in fish show that exposure to CB and OP can produce contrasting effects on the levels of brain catecholamines [12, 28].…”

Section: Discussionmentioning

confidence: 99%

Biochemical and behavioral effects of carbofuran in goldfish (Carassius auratus)

Bretaud¹,

Saglio²,

Saligaut³

et al. 2002

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

The effects of concentration (5, 50, and 500 microg/L) and duration (24, 48 h) of exposure to carbofuran, a carbamate insecticide, were assessed on brain catecholamine (norepinephrine [NE] and dopamine), plasma glucose, and hepatic glycogen contents and behavioral activities of goldfish (Carassius auratus). After 24 h of exposure to 50 and 500 microg/L, the level of NE was increased in the olfactory bulbs. The same effect was observed after a 48-h exposure to 500 and 50 microg/L in the telencephalic hemispheres and in the hypothalamus, respectively. An increase in the level of dopamine was also found in hypothalamus after 48 h of exposure to 500 microg/L carbofuran. Plasma glucose increased in concentration after both periods of exposure to carbofuran at 50 and 500 microg/L. Hepatic glycogen concentration decreased after a 48-h exposure to the highest concentration. Behavioral endpoints related to swimming pattern and social interactions were affected after a 24-h exposure to the lowest concentration tested (5 microg/L). The relative sensitivities of these different types of responses to exposure to carbofuran are discussed in light of data on the neurotoxic effects of carbamate and organophosphate insecticides in fish.

show abstract

Neurobehavioral changes in freshwater fishChanna punctatus exposed to fenitrothion

Cited by 8 publications

References 8 publications

Biochemical and Behavioral Effects of Carbofuran in Goldfish (Carassius Auratus)

Biochemical and Behavioral Effects of Carbofuran in Goldfish (Carassius Auratus)

Endocrine disruptors also function as nervous disruptors and can be renamed endocrine and nervous disruptors (ENDs)

Biochemical and behavioral effects of carbofuran in goldfish (Carassius auratus)

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