Neurobehavioral responses in swiss albino mice induced by an aqueous leaf extract from a medicinal plant named Heliotropium incanum ruiz & pav.

Abstract

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Datura metel stramonium exacerbates behavioral deficits, medial prefrontal cortex, and hippocampal neurotoxicity in mice via redox imbalance

“…To determine the anxiolytic properties of the extract on mice using the HBT, we adopted the procedure described by [ 86 ]. Each mouse was placed in the centre of the board and was allowed to explore the board freely for 10 min while tracking the number of times the mouse quickly dipped their heads into the holes (active dip).…”

“…Each mouse was placed in the centre of the board and was allowed to explore the board freely for 10 min while tracking the number of times the mouse quickly dipped their heads into the holes (active dip). After each test, the board was cleaned with 70% alcohol to remove odour signals [ 86 ] .…”