Neurobiological Mechanism of Acupuncture Analgesia in Chronic Somatic Pain

Yang, Wei; Chen, Teng; Zhang, Wen; Tian, Jia-He; Yang, Ya‐Chen; Wang, Yan-Qing

doi:10.1007/978-3-030-96221-0_16

Cited by 1 publication

(1 citation statement)

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“…Neuropathic pain : Pain resulting from damage to the nervous system characterized by burning, electrical shocks, shooting, and needle-type pain ( 36 , 37 ).…”

Section: Methodsmentioning

confidence: 99%

Breakthrough pain among cancer patients at oncology units in Northern Ethiopia; a multi-center study

Tekie,

Nigatu,

Mekonnen

et al. 2024

Front. Oncol.

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BackgroundBreakthrough cancer pain (BTCP) is a transient exacerbation of pain that affects the length of hospitalization and quality of life of patients. The objective of this study was to determine the prevalence and factors associated with BTCP among cancer patients at oncology units in Northern Ethiopia in 2022.MethodsA multi-center cross-sectional study was conducted from April to June 2022. After obtaining ethical approval, data were collected prospectively from 424 adult cancer patients admitted to oncology units. Breakthrough cancer pain was assessed by the numeric rating scale. Descriptive and binary logistic regression analyses were performed to determine the factors associated with BTCP. The strength of association was described in adjusted odds ratio (AOR) with 95% confidence intervals and variables with a P-value < 0.05 were considered to have a statistically significant association with BTCP.ResultThe prevalence of BTCP among cancer patients was 41.5%. The factors that were found to be associated with BTCP were colorectal cancer (AOR: 7.7, 95% CI: 1.8, 32.3), lung cancer (AOR: 6.9, 95% CI: 1.9, 26.0), metastasis (AOR: 9.3, 95% CI: 3.0, 29.1), mild background pain (AOR: 7.5, 95% CI: 2.5, 22.6), moderate background pain (AOR: 7.0, 95% CI: 2.2, 23.1), severe background pain (AOR: 7.1, 95% CI: 2.2, 22.8), no analgesics taken for background pain (AOR: 5.1, 95% CI: 2.8, 9.3) and uncontrolled background pain (AOR: 3.3, 95% CI: 1.8, 6.1).ConclusionThe prevalence of BTCP was high. Colorectal cancer, lung cancer, the presence of metastasis, the presence of background pain, not taking analgesics for background pain, and uncontrolled background pain were significantly associated with BTCP.

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“…Neuropathic pain : Pain resulting from damage to the nervous system characterized by burning, electrical shocks, shooting, and needle-type pain ( 36 , 37 ).…”

Section: Methodsmentioning

confidence: 99%