Neurochemical markers of cells of the periventricular brain area in the masu salmon Oncorhynchus masou (Salmonidae)

Pushchina, Ye. V.; Обухов, Д. К.; Вараксин, А. А.

doi:10.1134/s1062360412010055

Cited by 10 publications

(9 citation statements)

References 44 publications

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“…In adults O. masou, TH-labeling was found at the boundary separating pallial part of telencephalic hemispheres from subpallial one [27]. This is consistent with the data obtained for D. rerio, where it showed the presence of THimmunoreactive descendants of neuroblasts, migrated in the rostral migratory flow [33].…”

Section: Discussionsupporting

confidence: 89%

“…The results of our observations in different age groups of masu salmon showed that in the periventricular area of diencephalic, mesencephalic, medullary and spinal parts of brain are localized morphologically and neurochemically heterogeneous population of cells, some of which have processes and produce TH, GABA and NADPH-d/nNOS [27]. Study has shown that O. masou brain in different age periods contains proliferative zones (PZ) [28].…”

Section: Discussionmentioning

confidence: 66%

“…PCNA-labeling in the O. masou brain showed that yearling and adult individuals in the periventricular region of diencephalon and central gray layer of medulla oblongata show a population of proliferating cells [27]. At the level of forebrain the distribution of TH-ip cells corresponds to neuromeric structure of brain, which is confirmed by PCNA labeling of matrix zones.…”

Section: Discussionmentioning

confidence: 70%

“…Our results suggest that TH and NO may act as signaling molecules that regulate processes of adult neurogenesis in the diencephalon and other regions of brain of O. masou [28]. In diencephalon, tectum, medulla oblongata and spinal cord of three-, sixmonth and one-year-old juvenile of masu salmon in the periventricular cells synthesis of TH is defined [19,27]. In adults O. masou, TH marks periventricular cells with radially oriented outgrowths in diencephalon and medulla oblongata departments that have not previously been shown to fish.…”

Section: Discussionmentioning

confidence: 99%

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Undifferentiated Catecholaminergic and NO-Producing Cells of Forebrain Matrix Zones and Intercellular Relationships in Periventricular Diencephalon of Juvenile Oncorhynchus masou

Пущина¹

2015

AJBIO

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Localization of TH-and NO-producing systems in the diencephalon of juvenile masu salmon Oncorhynchus masou was investigated by using histofluorescence labeling of glyoxylic acid (GA), and ICH labeling of tyrosine hydroxylase (TH) and neuronal nitric oxide synthase (nNOS). High density distribution of catecholaminergic and NO-ergic cells has been found in preoptic, posterior tuberal and hypothalamic areas. Cells revealed in above mentioned diencephalic areas were assigned to three main types: pear-shaped, bipolar and rounded. Most of the TH-and NO-producing cells had the phenotype of undifferentiated elements localized on territory of diencephalic matrix zones. Paracrine and autocrine relationships between TH-and NO-producing cells in periventricular diencephalon of juvenile O. masou before formation of blood-brain barrier have been hypothesized. The lack of differentiated cells and the presence of a large variety of size groups of cells indicate a possible heterochrony in growth and differentiation of O. masou diencephalic areas. Location of catecholaminergic and NO-producing cells in the territory of diencephalic matrix zones suggests that catecholamines and nitric oxide are involved in the regulation of post-embryonic neurogenesis in diencephalon of O. masou.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Undifferentiated Catecholaminergic and NO-Producing Cells of Forebrain Matrix Zones and Intercellular Relationships in Periventricular Diencephalon of Juvenile Oncorhynchus masou

Пущина¹

2015

AJBIO

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“…In juvenile O. masоu has a high initial level of proliferation in the primary matrix zone of the brain (periventricular matrix zone) and proliferative activity in the zones, which have been identified in adult animals [13,14]. These data are diagnosed by immunolabeling of a proliferative cell nuclear antigen (PCNA), and using morphological methods to assess the number of mitoses in the matrix areas of brain.…”

Section: Discussionmentioning

confidence: 99%

Monitoring of Cell Migration and Apoptosis in Cerebellum of Juvenile Masu Salmon Oncorhynchus Masou After Injury

Stukaneva¹

2015

AJBIO

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Apoptosis in various cerebellar zones of juvenile masu salmon Oncorhynchus masou after mechanical injury was investigated by TUNEL-labeling. In the brain of 4 month-old juveniles of O. masou growth in different parts of cerebellum and proliferative activity in secondary matrix zones of cerebellum were continued. TUNEL-labeling was observed in the injured cerebellum 2 days after damage. The induction of proliferative activity in different matrix zones: granular eminences, dorsal part of molecular layer and surface layers of corpus cerebellum were noted. The proliferative activity in regional neurogenic niches is increased after injury of cerebellum. The maximal number of apoptotic elements in the cerebellum was observed in zones of the radial cell migration. We suggest that in damaged cerebellum both adult born cells and cells formed as a result of the reparative neurogenesis can be eliminated during radial migration as result of natural morphogenetic processes. Patterns of tangential and radial migration of cells were observed near the area of injury. The highest rate of apoptosis index was detected in the dorsal matrix zone corresponding to the zone of secondary neurogenesis. This testifies to the elimination of the newly formed cells at the stage of their localization in the matrix zones. The intensity of the apoptotic response varies in different areas of O. masou cerebellum.

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Neurochemical Organization and Connections of the Cerebral Preglomerular Complex of the Masu Salmon

Puschina

2012

Neurophysiology

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Using immunohistochemical labeling of the cells containing neuronal NO synthase (nNOS), tyrosine hydroxylase (TH), GABA, and parvalbumin (PA), as well as histochemical marking of choline acetyltransferase-containing neurons, we examined the neurochemical organization of the glomerular nuclei and preglomerular complex in the brain of the masu salmon (Oncorhynchus masou). Injections of the carbocyanine dye DiI allowed us to examine projections of neurons of the preglomerular and mammillary nuclei in the salmon brain. We showed that cholinergic, GABA-, PA-, TH-, and nNOS-immunopositive neurons belonging to different morphological types are present in the glomerular and medial preglomerular nuclei. The analysis of correlations between morphometric characteristics of the cells belonging to different neurochemical types and densitometric estimates of amounts of neurochemical agents present in these cells allowed us to hypothesize that there are close morphofunctional interrelations in cell populations possessing different neurochemical and morphometric characteristics. These interrelations of the cells belonging to different chemotypes are, probably, realized as mediatory/modulatory ones. The presence of a great number of small slightly differentiated cells in the preglomerular and glomerular nuclei allows us to suppose that the growth of the greatest sensory center of the salmon brain is provided by neuroblasts that migrate from the proliferative zones in the course of postembryonal neurogenesis. It is also hypothesized that NO, TH, and GABA are involved in paracrine control of the postnatal morphogenesis of the salmon preglomerular complex. The data obtained by hodological analysis indicate that the nuclei of the preglomerular complex obtain afferent projections from the dorsomedial and ventroventral telencephalic regions, preoptic nucleus, periventricular layer of the tectum, and posterior central thalamic nucleus. Our study demonstrated the existence of reciprocal functional connections between the preglomerular complex (most important diencephalic center for transmission of sensory information) and dorsomedial and ventral regions of the telencephalon in the masu salmon.

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Neurochemical markers of cells of the periventricular brain area in the masu salmon Oncorhynchus masou (Salmonidae)

Cited by 10 publications

References 44 publications

Undifferentiated Catecholaminergic and NO-Producing Cells of Forebrain Matrix Zones and Intercellular Relationships in Periventricular Diencephalon of Juvenile Oncorhynchus masou

Undifferentiated Catecholaminergic and NO-Producing Cells of Forebrain Matrix Zones and Intercellular Relationships in Periventricular Diencephalon of Juvenile Oncorhynchus masou

Monitoring of Cell Migration and Apoptosis in Cerebellum of Juvenile Masu Salmon Oncorhynchus Masou After Injury

Neurochemical Organization and Connections of the Cerebral Preglomerular Complex of the Masu Salmon

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