Neurocognition and community outcome in schizophrenia: long-term predictive validity

Interpersonal sensitivity and functioning impairment in youth at ultra-high risk for psychosis

“…Ratings for each of the two GF scales were based on available clinical information, which included clinician reports, telephone and face to face follow-up assessments. High inter-rater reliabilities (Fujii et al, 2003) were reported using this approach, along with construct and predictive validity (Cannon et al, 2008;Cornblatt et al, 2007).…”

Cognitive Deficits Caused by Late Gestational Disruption of Neurogenesis in Rats: a Preclinical Model of Schizophrenia

“…Cognitive deficits in memory, executive function, and working memory are believed to be of major importance to the functional and symptomatic outcome (Fujii and Wylie, 2003;Moritz et al, 2000;Grawe and Levander, 2001;Green et al, 2000) as well as the quality of life (Fujii et al, 2004) of patients with schizophrenia. Being able to address some of these symptoms in a preclinical model and consequently develop drugs that better target these symptoms could lead to better outcome and better quality of life for the patients.…”

Is Memory Impairment a Rate Limiter in Cognitive Behavioural Therapy for Chronic Schizophrenia?

“…Neurocognitive impairments in schizophrenia have been linked to treatment response, employment status, social relationships, living status, insight into illness, therapeutic alliance and community functioning [1] . Thus it is reasonable to suppose that cognitive impairment can also be a rate-limiting factor in some psychological treatments and that the severity of cognitive impairment may limit its clinical benefit as well [2] .…”