Neurocognitive deficits and history of childhood abuse in schizophrenia spectrum disorders: associations with Cluster B personality traits

Lysaker, Paul H.; Wickett, Amanda; Lancaster, Rebecca; Davis, Louanne W.

doi:10.1016/s0920-9964(03)00195-6

Cited by 33 publications

(14 citation statements)

References 56 publications

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“…Previous studies documented a large overlap between borderline personality disorder and dissociative disorders, including high frequencies of reported childhood trauma [43] . In a previous study on patients with schizophrenia, higher levels of borderline traits were uniquely related to the report of childhood sexual abuse [44] . It is possible that borderline personality disorder criteria represent a trauma-related symptom pattern among patients with schizophrenic disorder rather than a personality disorder per se.…”

Section: Discussionmentioning

confidence: 81%

Childhood Trauma and Dissociation in Schizophrenia

Şar

Taycan²,

Bolat³

et al. 2009

Psychopathology

131

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Background: This study is concerned with relationships between childhood trauma history, dissociative experiences, and the clinical phenomenology of chronic schizophrenia. Sampling and Methods: Seventy patients with a schizophrenic disorder were evaluated using the Structured Clinical Interview for DSM-IV, Dissociative Experiences Scale, Dissociative Disorders Interview Schedule, Positive and Negative Symptoms Scales, and Childhood Trauma Questionnaire. Results: Childhood trauma scores were correlated with dissociation scale scores and dissociative symptom clusters, but not with core symptoms of the schizophrenic disorder. Cluster analysis identified a subgroup of patients with high dissociation and childhood trauma history. The dissociative subgroup was characterized by higher numbers of general psychiatric comorbidities, secondary features of dissociative identity disorder, Schneiderian symptoms, somatic complaints, and extrasensory perceptions. A significant majority of the dissociative subgroup fit the diagnostic criteria of DSM-IV borderline personality disorder concurrently. Among childhood trauma types, only physical abuse and physical neglect predicted dissociation. Conclusions: A trauma-related dissociative subtype of schizophrenia is supported. Childhood trauma is related to concurrent dissociation among patients with schizophrenic disorder. A duality model based on the interaction of 2 qualitatively distinct psychopathologies and a dimensional approach are proposed as possible explanations for the complex relationship between these 2 psychopathologies and childhood trauma.

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Section: Discussionmentioning

confidence: 81%

Childhood Trauma and Dissociation in Schizophrenia

Şar

Taycan²,

Bolat³

et al. 2009

Psychopathology

131

View full text Add to dashboard Cite

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“…The authors suggest that understanding troublesome behaviours in the context of past traumatic events can help clinicians become more compassionate towards patients with BPD. As trauma is also a documented risk factor for concomitant psychosis and BPD (Kingdon et al, 2008;Lysaker et al, 2004), this empathy-increasing strategy might be not only clinically useful, but also scientifically based.…”

Section: Discussionmentioning

confidence: 99%

“…Despite the controversy surrounding the existence of individuals with both a psychotic disorder and BPD, the literature consistently finds a prevalence of 10-20% of individuals with a psychotic disorder also having a BPD diagnosis, and a similar prevalence of individuals with BPD meeting the symptomatic criteria for an Axis I psychotic disorder, (Coid et al, 2009;Dowson, Sussams, Grounds, & Taylor, 2000;Glaser, Van Os, Thewissen, & Meyers-Germeys, 2010;Kingdon et al, 2010;Lysaker, Wickett, Lancaster, & Davis, 2004;Nishizono-Maher, Ikuta, Ogiso, Moriya, & Miyake, 1993;Pope, Jonas, Hudson, & Cohen, 1985;Wickett et al, 2006;Zanarini, Gunderson, & Frankenburg, 1990). …”

Section: Introductionmentioning

confidence: 99%

The experience of treatment of persons with concomitant psychotic and borderline personality disorders

et al. 2012

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The present study investigated the treatment experience of nine individuals with concomitant psychotic and borderline personality disorders. Given the paucity of research on the experience of this population, the goal was to explore pathways to care, transitions between services and general perception of treatments using a qualitative methodology. A semi-structured interview schedule was administered to each participant, who was referred by participating psychiatrists in each program. Transcripts were coded using a mixed open and closed coding procedure and QDA Miner 3.2.3 analysis software. Results found that participants did not dichotomise their experience into all-good or all-bad categories, but gave nuanced accounts of their treatment. Each participant described several pathways to care that explained their entry into specific treatments, with only coercion negatively impacting treatment experience. Many transitions were described, though only those who were coerced experienced these negatively. The key factor that participants highlighted in their treatment experience was the clinician/participant relationship. A positive relationship permitted participants to trust and receive help from their clinician. Limits include the possible bias of the recruitment procedure and the limited scope of the study. This understanding of the perspective of these individuals can lead to promoting better treatment experiences in the future. IntroductionThere is a paucity of research on the co-occurrence of psychosis and borderline personality disorder (BPD) (Kingdon et al., 2010). Despite the controversy surrounding the existence of individuals with both a psychotic disorder and BPD, the literature consistently finds a prevalence of 10-20% of individuals with a psychotic disorder also having a BPD diagnosis, and a similar prevalence of individuals with BPD meeting the symptomatic criteria for an Axis I psychotic disorder, (Coid et al.,

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“…The findings indicate that similar neurotransmitter systems are dysfunctional in BPD and psychosis. These overlapping findings may originate from traumatic experiences in schizophrenia and BPD patients [61]. Table 1 displays the neurobiological findings in BPD and schizophrenia.…”

Section: Pathophysiologymentioning

confidence: 99%

Borderline Personality Disorder and Psychosis: A Review

Barnow

Arens

Sieswerda

et al. 2010

Curr Psychiatry Rep

104

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Early views of borderline personality disorder (BPD) were based on the idea that patients with this pathology were "on the border" of psychosis. However, more recent studies have not supported this view, although they have found evidence of a malevolent interpersonal evaluation and a significant proportion of BPD patients showing psychotic symptoms. For example, in one study, 24% of BPD patients reported severe psychotic symptoms and about 75% had dissociative experiences and paranoid ideation. Thus, we start with an overview regarding the prevalence of psychotic symptoms in BPD patients. Furthermore, we report findings of studies investigating the role of comorbidity (eg, post-traumatic stress disorder) in the severity and frequency of psychotic symptoms in BPD patients. We then present results of genetic and neurobiological studies comparing BPD patients with patients with schizophrenia or nonschizophrenic psychotic disorders. In conclusion, this review reveals that psychotic symptoms in BPD patients may not predict the development of a psychotic disorder but are often permanent and severe and need careful consideration by clinicians. Therefore, adequate diagnosis and treatment of psychotic symptoms in BPD patients is emphasized.

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Neurocognitive deficits and history of childhood abuse in schizophrenia spectrum disorders: associations with Cluster B personality traits

Cited by 33 publications

References 56 publications

Childhood Trauma and Dissociation in Schizophrenia

Childhood Trauma and Dissociation in Schizophrenia

The experience of treatment of persons with concomitant psychotic and borderline personality disorders

Borderline Personality Disorder and Psychosis: A Review

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