Neurocognitive dysfunction among type 2 diabetes patients attending primary health care in Jeddah, Saudi Arabia

Alshaikh, AlshaymaaA; Alatawi, HindS; Alzahrani, AbdullahM

doi:10.4103/jfmpc.jfmpc_423_21

Cited by 2 publications

(6 citation statements)

References 34 publications

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“…Our results demonstrated that 12.1% of the participants suffered from severe cognitive dysfunction. These ndings are consistent with previous research examined the prevalence of severe cognitive impairment in adult diabetic patients (27). According to a study conducted in Riyadh, Saudi Arabia, the prevalence of severe cognitive impairment was 33.8% (7), which was higher than the prevalence of our ndings.…”

Section: Discussionsupporting

confidence: 92%

“…Logistic regression analysis also revealed that patients with long duration of diabetes reported signi cantly poor cognitive ability. The present study supports the previous ndings regarding the relationship of duration of diabetes and cognitive functions (24,27,(40)(41)(42). Kalar,et al (43), reported that patients with long history of diabetes showed poor performance in recent memory, repetition and attention test as compare to control group.…”

Section: Discussionsupporting

confidence: 92%

“…Similar to the ndings in this study, Kataria, I. et al (32) reported that the prevalence of cognitive impairment was 35.6% among diabetic patients using MMSE, with two-thirds of cases having mild cognitive impairment. The prevalence of cognitive impairment in the present study is comparable to study conducted in Jeddah, Saudi Arabia (27). Another study conducted in Saudi Arabia using the Montreal Cognitive Assessment test found that 45% of diabetic patients (aged > 60 years) had cognitive impairment, with 38.6% having mild cognitive impairment and 6.4% having dementia (28).…”

Section: Discussionsupporting

confidence: 79%

“…According to previously published studies, the prevalence of cognitive dysfunction in Saudi Arabia's diabetic population could range from 35.2-80.3%. (7,27). This sample size was calculated with a precision/absolute error of 5% and a type 1 error of 5%.…”

Section: Study Samplementioning

confidence: 99%

“…The recent studies conducted in Saudi Arabia reported the prevalence of cognitive impairment in diabetic patients were 35.2% (27), 45% (28) and 80.3% (7). However, which cognitive domain is most affected in diabetic patients is still up for debate (18).…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and Determinants of Cognitive Dysfunction among Patients with Diabetes in Eastern Saudi Arabia

Lone

Pathath

2023

Preprint

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Background: Cognitive dysfunction is recognized as a major diabetes comorbidity and complication that affects an individual's well-being. Recent studies demonstrated that diabetic patients have a higher incidence of cognitive dysfunction. As a result, new diabetes management guidelines recommend screening for cognitive impairments in older diabetics. Objectives: This study aims to explore the prevalence and potential risk of cognitive dysfunction in diabetic patients. Method: This cross-sectional study was conducted from June to November, 2022 where 257 patients with diabetes were selected byconvenient sample technique. Cognitive dysfunction was measured by using Mini-mental state examination (MMSE). Sociodemographic, diabetes related and clinical factors were analyzed as cofactors of cognitive dysfunction. Result: The findings of the study revealed that 38.9% of participants had cognitive dysfunction while 12.1% had severe cognitive dysfunction. The domain of delayed recall was the most affected, while language/praxis was least affected domain of MMSE. Duration of diabetes was inversely associated with cognitive dysfunction. Results of logistic regression analysis revealed low level of education (OR = 4.95; p =.043) and more duration of diabetes (OR = 6.08; p =.010) were independently associated with severe cognitive impairment. Conclusion: Diabetes patients in their middle and advanced years are particularly vulnerable to cognitive decline. Therefore, healthcare professionals and family physicians should focus more on detecting cognitive decline in the early stages of diabetes mellitus.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 79%

Section: Study Samplementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Prevalence and Determinants of Cognitive Dysfunction among Patients with Diabetes in Eastern Saudi Arabia

Lone

Pathath

2023

Preprint

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Neurocognitive impairment and its associated factors among patients with diabetes mellitus who have follow up at referral hospital in Northwest, Ethiopia

Simachew,

Getnet,

Minwuyelet

et al. 2024

Front. Endocrinol.

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BackgroundNeurocognitive impairment is a condition that makes it difficult for a person to make decisions that affect memory, learning new things, concentration on daily activities, and can range from mild to severe forms. It is a major health problem, less known and less addressed complication of diabetes mellitus.ObjectivesThe aim of the study is to assess prevalence of neurocognitive impairment and associated factors among diabetic mellitus patients.MethodsWe conducted an institutional-based cross-sectional study involving 512 diabetic patients under follow-up at XXX Specialized Hospital from March 1 to April 30, 2023. Data on cognition, behavior, and depression were collected using standardized tools, including the Mini Mental State Examination for cognition, the CAGE assessment tool for alcohol-related behavior, and the PHQ-9 for depression. These assessments were conducted through face-to-face interviews and chart reviews. A diagnosis of diabetes is confirmed in adults when fasting blood glucose levels exceed 126 mg/dl in three consecutive follow-up measurements. Data entry was performed using Epidata version 4.6, and analysis was conducted using SPSS version 26. Variables with a P-value < 0.25 in bivariate analysis were included in multivariable logistic regression. Statistical significance was set at P ≤ 0.05 with a 95% CI. Results were presented using tables, graphs, and descriptive text.ResultsThe prevalence of neurocognitive impairment among diabetic patients at XXX Comprehensive Specialized Hospital was 28.3% [95% CI: 24.57–32.39]. Factors associated with this impairment included being female (AOR=2.29 [95% CI: 1.43-3.67]), rural residence (AOR=3.16 [95% CI: 2.01-4.95]), comorbidity (AOR=3.30 [95% CI: 2.08-5.23]), diabetes duration of 6-10 years (AOR=1.72 [95% CI: 1.01-2.94]), diabetes duration >10 years, and blood sugar level >126 mg/dl (AOR=2.25 [95% CI: 1.42-3.57]). Patients are encouraged to adhere to proper medication regimens to effectively control their blood glucose levels. This study found a high prevalence of neurocognitive impairment (NCI) among diabetic patients, affecting about one-fourth based on MMSE scores. Key risk factors identified include female gender, rural residence, comorbidities, longer duration of diabetes, and elevated blood glucose levels.

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Neurocognitive dysfunction among type 2 diabetes patients attending primary health care in Jeddah, Saudi Arabia

Cited by 2 publications

References 34 publications

Prevalence and Determinants of Cognitive Dysfunction among Patients with Diabetes in Eastern Saudi Arabia

Prevalence and Determinants of Cognitive Dysfunction among Patients with Diabetes in Eastern Saudi Arabia

Neurocognitive impairment and its associated factors among patients with diabetes mellitus who have follow up at referral hospital in Northwest, Ethiopia

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