2003
DOI: 10.1089/088922203322280856
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Neurocognitive Performance and Quality of Life in Patients with HIV Infection

Abstract: We examined the relationship of HIV-related cognitive impairment and health-related quality of life (QoL). Subjects were administered measures of cognitive function (a battery of 17 neuropsychological tests) and of QoL (the MOS-HIV questionnaire). Study measures also included comprehensive clinical and neurological evaluation, laboratory testing, and brain imaging studies in patients with impaired neuropsychological evaluation. One-hundred and eleven subjects were examined. Cognitively impaired patients (33.3%… Show more

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Cited by 112 publications
(111 citation statements)
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“…The tentative answer is "yes." Cognitive dysfunction is associated with a diminished quality of life [15]. Thus, a valid argument can be made for clinical trials in patients with SCLC in an effort to improve cognition and perhaps also quality of life.…”
Section: Discussionmentioning
confidence: 99%
“…The tentative answer is "yes." Cognitive dysfunction is associated with a diminished quality of life [15]. Thus, a valid argument can be made for clinical trials in patients with SCLC in an effort to improve cognition and perhaps also quality of life.…”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, neuropsychological deficits still exist in a substantial proportion of patients despite ARV treatment (15%-50%) [1••, 2]. The persistence of neurocognitive dysfunction in HIV-infected patients is an important issue given its debilitating nature and the negative effects on an individual's overall quality of life [7], ability to perform activities of daily living [8], employment [9], and medication adherence [10,11].…”
Section: Neurocognitive Dysfunction Despite Successful Treatmentmentioning
confidence: 99%
“…Portanto é importante reconhecer precocemente danos sutis, já que, em alguns casos, podem significativamente melhorar a chance de reversão da demência com HAART 5 , melhorar a qualidade de vida com tratamentos adicionais 46 e mesmo possibilitar a monitorização da aderência do paciente à medicação. Além do fato de poder melhorar a orientação para os familiares sobre as alterações comportamentais e cognitivas do paciente.…”
Section: Diagnóstico Das Alterações Cognitivas Da Aidsunclassified