Neurodegeneration and the Gothenburg MCI study

Abstract

Mild cognitive impairment (MCI) is the stage between the expected cognitive decline of a normal aging population and the more serious decline of dementia. Typically, the performance of a cognitive test is considered impaired if it is =>1.5 standard deviations below normal controls. The ongoing Gothenburg mild cognitive impairment (MCI) study is an attempt to conduct longitudinal in-depth phenotyping of patients with different forms and degrees of cognitive impairment using various assessment tools. This paper presents the background of the linguistic and extra-linguistic parameters for early detection of cognitive impairment-project, a research which is partly based on data acquired at the Gothenburg MCI-study.