Neurofibroma in a Patient With von Recklinghausen??s Disease Seen as a Malignant Schwannoma

Schwannoma maligno em pacientes com doença de von Recklinghausen: relato de dois casos

“…Malignant transformation varies between 2% and 40%, and these patients are more prone to having malignant tumors of the nervous tissues and other secondary neoplasias 1 . They tend to appear in young patients in the middle of their bodies, and these patients run a high risk of having the tumors turn malignant -of worse prognoses and happening earlier on when compared to neurofibromas alone 1,3,4 .…”

“…Malignancy must be suspected when there is a fast growing and painful mass, investigated by image exams (CT, MRI, Bone Scintigraphy and Angiography) for staging, resection evaluation and lesion biopsy purposes 3 . Benign lesions can also show fast growth 3,5 .…”