Neurofilament Light Chain Is Associated With Acute Mountain Sickness
Klaus Berek,
Anna Lindner,
Franziska Di Pauli
et al.
Abstract:BackgroundNeurological symptoms are common in acute mountain sickness (AMS); however, the extent of neuroaxonal damage remains unclear. Neurofilament light chain (NfL) is an established blood biomarker for neuroaxonal damage.ObjectiveTo investigate whether plasma (p) NfL levels increase after simulated altitude exposure, correlate with the occurrence of AMS, and might be mitigated by preacclimatization.MethodsHealthy subjects were exposed to simulated high altitude (4500 m) by the use of a normobaric hypoxic c… Show more
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