Neuroimaging and Genetic Influence in Treating Brain Neoplasms

Cruz, Luiz Celso Hygino da; Kimura, Margareth

doi:10.1016/j.nic.2014.09.011

Cited by 6 publications

(2 citation statements)

References 55 publications

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“…These neoplasms represent some of the deadliest malignant tumors, are refractory to treatment and impact the quality of life of patients and caregivers 1 . Estimated worldwide incidence is 10.82 per 100,000 population every year, with intracranial metastases being up to 10 times more common than primary neoplasms 2,3 , followed in frequency by meningiomas and gliomas with an incidence of 7.72 and 3.2 per 100,000 population, respectively [4][5][6] . Glioblastoma (GBM), previously known as glioblastoma multiforme due to its complex histological image, represents the most common primary malignant tumor of the CNS, accounting for 16% of all primary intracranial neoplasms, but for 45.6% of the malignant ones 7,8 .…”

Section: Introductionmentioning

confidence: 99%

Tumores primarios de alto grado del sistema nervioso central: análisis clínico y epidemiológico de la experiencia de un centro

García-Espinosa¹,

Botello-Hernández²,

Pérez-García³

et al. 2022

GAMO

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Background: Epidemiological data on the clinical presentation of high-grade primary tumors, the most common histological variables and prevalence, and sociodemographic variables were addressed from January 2016 to December 2020. Method: The sample was calculated from the primary tumors provided by the statistics department, determined the ICD-10 (C-71), finding 105. Results: 114 cases of high-grade primary tumors, most of them men; glioblastoma was the most common variant, followed by medulloblastoma. The frontal lobe was the most common location, consultation times lasted between 3-6 months, the most common clinical symptom was headache; the most common reason for consultation were seizures. Conclusion:The paradigm shift in the treatment of primary brain tumors from a molecular profile, and not precisely histological, will be the next step to take. These tumors are of great epidemiological importance and an opportunity to carry out preventive medicine and health promotion campaigns.

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Section: Introductionmentioning

confidence: 99%

Tumores primarios de alto grado del sistema nervioso central: análisis clínico y epidemiológico de la experiencia de un centro

García-Espinosa¹,

Botello-Hernández²,

Pérez-García³

et al. 2022

GAMO

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“…Of the glial tumors, GBM is the most frequent, representing approximately 50–60% of astrocytomas [6]. The prognosis of GBM is dismal, with a survival rate less than one year despite current therapeutic advances.…”

Section: Discussionmentioning

confidence: 99%

Fourth Ventricular Lesions in Metastatic Gliomas: A Rare Predilection?

Khan

Poulin

Essig

2017

Brain Tumor Res Treat

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Over the course of five years, a total of ten cases were collected of glioma patients in whom a distant lesion at the fourth ventricle was noted. A ‘distant lesion’ was defined as a lesion with a normal appearing tissue bridge at imaging between the primary and secondary locations. Previous imaging of these patients was reviewed along with clinical history, course of therapy, and available histology. A review of the literature was performed with respect to present knowledge on patterns of glioma proliferation and dissemination. This case series is the first to describe the fourth ventricle as a location that may be prone to secondary lesions in glioma patients. Further investigation on this subject may yield deeper insights into the mechanisms by which glial tumors spread within the brain, with the hope of developing or improving therapeutic targets.

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Diffusion magnetic resonance imaging in brain tumours

Corrêa

Cruz

2022

Handbook of Neuro-Oncology Neuroimaging

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Neuroimaging and Genetic Influence in Treating Brain Neoplasms

Cited by 6 publications

References 55 publications

Tumores primarios de alto grado del sistema nervioso central: análisis clínico y epidemiológico de la experiencia de un centro

Tumores primarios de alto grado del sistema nervioso central: análisis clínico y epidemiológico de la experiencia de un centro

Fourth Ventricular Lesions in Metastatic Gliomas: A Rare Predilection?

Diffusion magnetic resonance imaging in brain tumours

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