Neuroimaging characteristics and growth pattern on magnetic resonance imaging in a 52-year-old man presenting with pituicytoma: a case report

Kosuge, Yasushi; Hiramoto, Jun; Morishima, Hiroyuki; Tanaka, Yuichiro; Hashimoto, Tsuyoshi

doi:10.1186/1752-1947-6-306

Cited by 12 publications

(3 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is no recurrence after total resection and varying degrees recurrence of subtotal resection. A recent report demonstrated that the doubling time of tumor volume is about 7 years . The main reason for incomplete resection is due to intraoperative bleeding, which was exactly the case for our first surgery.…”

Section: Discussionsupporting

confidence: 53%

A 30‐Year‐Old Female with a Suprasellar Tumor

Zhang

Huang

et al. 2015

Brain Pathology

View full text Add to dashboard Cite

A 30-year-old female has experienced amenorrhea and progressive loss of vision for 4 years. Physical examinations were normal except bitemporal hemianopsia revealed by ophthalmic examination. Preoperative neuroendocrine examinations showed a mild hyperprolactinemia of 72.3 ng/mL (normal range, 2.8 ng/mL-29.2 ng/mL). MRI scan revealed a 31 mm 3 34 mm 3 31 mm wellcircumscribed roundness mass in the suprasellar region, with intermediate signal intensity on T1-weighted images, intermediate to slightly increased signal intensity on T2-weighted images and homogeneous enhancement with gadolinium administration with obviously homogeneous enhancement after gadolinium administration ( Figure 1A). Extended endoscopic endonasal transsphenoidal approach was chosen to resect the tumor. Intraoperatively, we encountered active bleeding, however, the bleeding stopped after the tumor was completely resected. Postoperative, the patient had serious diabetes insipidus and electrolyte disturbance. Blood sodium was as high as 190 mmol/L (normal range, 135 mmol/L-145 mmol/L). After comprehensive treatment, the diabetes insipidus was cured and blood sodium became normal. Three months after endoscopic surgery, MRI examination revealed that the tumor was completely removed ( Figure 1B).

show abstract

Section: Discussionsupporting

confidence: 53%

A 30‐Year‐Old Female with a Suprasellar Tumor

Zhang

Huang

et al. 2015

Brain Pathology

View full text Add to dashboard Cite

show abstract

“…Pituicytomas are exceedingly rare non-neuroendocrine neoplasms in the sellar or suprasellar region, originating from the neurohypophysis or infundibulum [1]. The tumors are histologically benign, but their ample vascular characteristics make complete resection difficult, and local recurrence or progression following partial resection is not uncommon [2][3][4][5]. Management of pituicytoma remains a controversial issue due to its rarity and lack of a large series of cases describing the adverse factors for tumor progression.…”

Section: Introductionmentioning

confidence: 99%

Treatment and prognostic factors of pituicytoma: a single-center experience and comprehensive literature review

Wei

et al. 2021

Pituitary

View full text Add to dashboard Cite

Purpose Preoperative diagnosis of pituicytomas is difficult, and management and prognostic factors remain ambiguous. The purpose of this study was to elucidate the radiological characteristics of pituicytoma, to assess the risk factors affecting tumor progression, and to propose the optimal treatment regimen based on comprehensive analysis. Methods We reviewed the clinical data of 22 patients with pituicytoma confirmed pathologically in our institution. In addition, 93 cases of pituicytoma in the previous literature were recruited. The individual data of 115 patients were analyzed to evaluate the adverse factors affecting pituicytoma progression. Results In the combined cohort, 3 of 61 patients who underwent gross-total resection (GTR) developed recurrence (4.9%); of the 54 patients who received non-GTR, 19 progressed (35.2%). Univariate and multivariate Cox regression analysis verified male gender (HR 2.855, 95% CI 1.008–8.089; p = 0.048), TS (transsphenoidal surgery; HR 3.559, 95% CI 1.015–12.476; p = 0.047), and non-GTR (HR 4.388, 95%CI 1.240–15.521; p = 0.022) were independent unfavorable factors for pituicytoma progression. A multivariate logistic regression model verified that tumor diameter ≥ 1.85 cm (OR 4.859, 95% CI 1.335–17.691; p = 0.016) was independent adverse factors for GTR. Compared with TS, OT (open transcranial) is more likely to have postoperative complications (OR 3.185, 95% CI 1.020–9.944; p = 0.046), especially vision deterioration (OR 37.267, 95% CI 4.486–309.595; p = 0.001). Conclusion Based on our findings, GTR was advocated as an optimal treatment for pituicytomas. However, in order to avoid damage to important structures, partial resection is acceptable. After that, adjuvant radiotherapy is recommended for male patients with high Ki-67 index, and the remaining patients can be followed up closely. When the tumor recurs or progresses, it is recommended to re-operate and remove the lesion completely as far as possible. If GTR is still not possible, postoperative radiotherapy for the residual tumor is recommended.

show abstract

“…El pituicitoma es una neoplasia selar rara, sólida, con contornos definidos y de bajo grado (clasificación de la organización mundial de la salud (OMS) grado I), proveniente del tejido glial o de sostén (pituicitos) ubicado en las zonas perivasculares de la neurohipófisis (3)(4)(5) .…”

Section: Introductionunclassified

Impresión diagnóstica clínico-radiológica de pituicitoma, presentación de dos casos clínicos

Lucero

Niño

Rojas

et al. 2017

Rev.ACE

View full text Add to dashboard Cite

Pituicitoma es un tumor único de bajo grado, originado en las células magnocelulares de la neurohipófisis, o en el infundíbulo. Es una entidad rara, que afecta a los adultos. Las manifestaciones clínicas dependen de la localización y el tamaño, pudiendo simular un adenoma hipofisiario, pues también puede comprometer cualquier eje hipofisiario. El diagnóstico se realiza por medio de resonancia magnética nuclear (RMN) y biopsia, y su tratamiento puede ser por medio de medicamentos o cirugía.En este articulo presentamos dos casos clínicos de dos adultos con pituicitoma, quienes tuvieron hallazgos radiológicos similares.Abstract Pituicytoma is an only low-grade tumor which is originated from magnocellular cells in neurohypophysis or in infundibulum. It is a rare condition that affects adults. The clinical manifestations depends on the location and size because it is similar to a pituitary adenoma, so it produces nonspecific damage to the pituitary axis. For the diagnosis is usually performed with Magnetic Resonance Imaging (MRI) and biopsy and treatment of this disease may be with drugs or surgery.In this article we show two clinical cases of two adults with pituicytoma who had similar radiological findings.

show abstract

Neuroimaging characteristics and growth pattern on magnetic resonance imaging in a 52-year-old man presenting with pituicytoma: a case report

Cited by 12 publications

References 13 publications

A 30‐Year‐Old Female with a Suprasellar Tumor

A 30‐Year‐Old Female with a Suprasellar Tumor

Treatment and prognostic factors of pituicytoma: a single-center experience and comprehensive literature review

Impresión diagnóstica clínico-radiológica de pituicitoma, presentación de dos casos clínicos

Contact Info

Product

Resources

About