2015
DOI: 10.1177/1971400915609344
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Neuroimaging evaluation in refractory epilepsy

Abstract: Neuroimaging studies allow the assessment of functional and structural damage related to epileptogenic lesions and foci, and are helpful to select surgical treatment, conduct intraoperative neuronavigation techniques, predict surgical deficits and evaluate patient recovery.

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Cited by 7 publications
(11 citation statements)
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“…MTS is the main cause of refractory epilepsy; regarding the final report of the institutional review board of epilepsy, MTS was diagnosed in 55.5% (25/45) of all epilepsy patients, which is related to reports in the literature. 2,9,10 The main imaging findings of MTS are decreases in the size of the hippocampus with signal alteration on T2-weighted sequences. 1114 Conventional MRI, even with high-resolution thin sequences, has reported low predictive values with a sensitivity of 42% and specificity of 80% in the identification of hippocampal atrophy with a high proportion of false negatives; 2,11 they tend to improve in patients with moderate and severe MTS, where values have been reported of sensitivity up to 93% and specificity of 98%.…”
Section: Discussionmentioning
confidence: 99%
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“…MTS is the main cause of refractory epilepsy; regarding the final report of the institutional review board of epilepsy, MTS was diagnosed in 55.5% (25/45) of all epilepsy patients, which is related to reports in the literature. 2,9,10 The main imaging findings of MTS are decreases in the size of the hippocampus with signal alteration on T2-weighted sequences. 1114 Conventional MRI, even with high-resolution thin sequences, has reported low predictive values with a sensitivity of 42% and specificity of 80% in the identification of hippocampal atrophy with a high proportion of false negatives; 2,11 they tend to improve in patients with moderate and severe MTS, where values have been reported of sensitivity up to 93% and specificity of 98%.…”
Section: Discussionmentioning
confidence: 99%
“…2,9,10 The main imaging findings of MTS are decreases in the size of the hippocampus with signal alteration on T2-weighted sequences. 1114 Conventional MRI, even with high-resolution thin sequences, has reported low predictive values with a sensitivity of 42% and specificity of 80% in the identification of hippocampal atrophy with a high proportion of false negatives; 2,11 they tend to improve in patients with moderate and severe MTS, where values have been reported of sensitivity up to 93% and specificity of 98%. 13 Different factors associated with the technique and the patients mean that the qualitative analysis is susceptible to false negatives, even for expert neuroradiologists.…”
Section: Discussionmentioning
confidence: 99%
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“…Başarısız cerrahi sonrası yeniden opere edilecek hastalarda özellikle de diğer görüntüleme yöntemlerinin arada kaldığı olgularda nöro-görüntüleme çalışmaları mutlak gereklidir (21,22). Ancak eğer MR bulguları ile iktal kafatası EEG bulguları uyumlu ise PET yeni bir veri sağlamazken MR'ı normal ve EEG bulguları karmaşık ise PET bulguları iyi cerrahi sonuç için yüksek prediktif değere sahiptir (23,24).…”
Section: Epilepsiodağınagörealttiplerunclassified