Neuroimaging with near-infrared spectroscopy demonstrates speech-evoked activity in the auditory cortex of deaf children following cochlear implantation

Sevy, Alexander; Bortfeld, Heather; Huppert, Theodore J.; Beauchamp, Michael S.; Tonini, Ross; Oghalai, John S.

doi:10.1016/j.heares.2010.09.010

Cited by 104 publications

(109 citation statements)

References 59 publications

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“…However, because CI devices are generally incompatible with established neuroimaging techniques including fMRI, the ability to study preimplant to postimplant crossmodal plasticity underlying hearing restoration with a CI has been severely limited (7). Here we overcame these technical challenges by using an emerging optical technique, functional near-infrared spectroscopy (fNIRS), which offers full compatibility with CI devices (11) and is safe for repeated testing. This enabled us to directly examine changes in cross-modal activation of auditory brain regions by visual speech from before to after cochlear implantation and its relation to CI success.…”

Section: Significancementioning

confidence: 99%

Adaptive benefit of cross-modal plasticity following cochlear implantation in deaf adults

Anderson

Wiggins

Kitterick

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

118

134

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It has been suggested that visual language is maladaptive for hearing restoration with a cochlear implant (CI) due to cross-modal recruitment of auditory brain regions. Rehabilitative guidelines therefore discourage the use of visual language. However, neuroscientific understanding of cross-modal plasticity following cochlear implantation has been restricted due to incompatibility between established neuroimaging techniques and the surgically implanted electronic and magnetic components of the CI. As a solution to this problem, here we used functional near-infrared spectroscopy (fNIRS), a noninvasive optical neuroimaging method that is fully compatible with a CI and safe for repeated testing. The aim of this study was to examine cross-modal activation of auditory brain regions by visual speech from before to after implantation and its relation to CI success. Using fNIRS, we examined activation of superior temporal cortex to visual speech in the same profoundly deaf adults both before and 6 mo after implantation. Patients' ability to understand auditory speech with their CI was also measured following 6 mo of CI use. Contrary to existing theory, the results demonstrate that increased cross-modal activation of auditory brain regions by visual speech from before to after implantation is associated with better speech understanding with a CI. Furthermore, activation of auditory cortex by visual and auditory speech developed in synchrony after implantation. Together these findings suggest that cross-modal plasticity by visual speech does not exert previously assumed maladaptive effects on CI success, but instead provides adaptive benefits to the restoration of hearing after implantation through an audiovisual mechanism. cochlear implantation | cross-modal plasticity | functional near-infrared spectroscopy | superior temporal cortex | visual speech

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Section: Significancementioning

confidence: 99%

Adaptive benefit of cross-modal plasticity following cochlear implantation in deaf adults

Anderson

Wiggins

Kitterick

et al. 2017

Proc. Natl. Acad. Sci. U.S.A.

118

134

View full text Add to dashboard Cite

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“…Also fNIRS provides silent recordings that are free from magnetic and electrical artefacts, and thus is highly suited to auditory research and is safe for repeated use in CI recipients (Sevy et al, 2010). Further, it is possible to measure functional responses to auditory stimulation in auditory cortex using fNIRS (Ohnishi et al, 1997;Minagawa-Kawai et al, 2002;Remijn and Kojima, 2010;Sevy et al, 2010;Plichta et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

Cortical cross-modal plasticity following deafness measured using functional near-infrared spectroscopy

Dewey

Hartley

2015

Hearing Research

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Evidence from functional neuroimaging studies suggests that the auditory cortex can become more responsive to visual and somatosensory stimulation following deafness, and that this occurs predominately in the right hemisphere. Extensive cross-modal plasticity in prospective cochlear implant recipients is correlated with poor speech outcomes following implantation, highlighting the potential impact of central auditory plasticity on subsequent aural rehabilitation. Conversely, the effects of hearing restoration with a cochlear implant on cortical plasticity are less well understood, since the use of most neuroimaging techniques in CI recipients is either unsafe or problematic due to the electromagnetic artefacts generated by CI stimulation. Additionally, techniques such as functional magnetic resonance imaging (fMRI) are confounded by acoustic noise produced by the scanner that will be perceived more by hearing than by deaf individuals. Subsequently it is conceivable that auditory responses to acoustic noise produced by the MR scanner may mask auditory cortical responses to non-auditory stimulation, and render inter-group comparisons less significant. Uniquely, functional near-infrared spectroscopy (fNIRS) is a silent neuroimaging technique that is non-invasive and completely unaffected by the presence of a CI. Here, we used fNIRS to study temporal-lobe responses to auditory, visual and somatosensory stimuli in thirty profoundly-deaf participants and thirty normally-hearing controls. Compared with silence, acoustic noise stimuli elicited a significant group fNIRS response in the temporal region of normally-hearing individuals, which was not seen in profoundly-deaf participants. Visual motion elicited a larger group response within the right temporal lobe of profoundly-deaf participants, compared with normally-hearing controls. However, bilateral temporal lobe fNIRS activation to somatosensory stimulation was comparable in both groups. Using fNIRS these results confirm that auditory deprivation is associated with cross-modal plasticity of visual inputs to auditory cortex. Although we found no evidence for plasticity of somatosensory inputs, it is possible that our recordings may have included activation of somatosensory cortex that masked any group differences in auditory cortical responses due to the limited spatial resolution associated with fNIRS.

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“…This method has been employed to study the functional development of the cortex in children and adults. Therefore, NIRS is a useful technique in this regard, non-invasive, easy to apply, tolerant to slight movements, which may be a complement to other existing techniques such as electroencephalogram, magnetoencephalography, functional magnetic resonance imaging to study the brain development in children 2,3,15,16 .…”

Section: Discussionmentioning

confidence: 99%

“…The Near-infrared spectroscopy (NIRS) is a promising tool, and has been used to assess the functional activation of the brain in children. This technology uses sources of visible light in the near-infrared electromagnetic spectrum range and evaluates photosensitive molecular components of the biological tissue 1,2 . Part of the near-infrared light is diverted and the other part is absorbed by the studied tissue.…”

Section: Introductionmentioning

confidence: 99%

“…It has a good spatial resolution and better temporal resolution compared with Functional Magnetic Resonance Imaging. It has been successfully employed in the presentation of auditory stimuli for investigation of the auditory skills in newborns and young infants 2,[7][8][9][10] . Normally the coupling of the optodes in the head, reduction of artifacts in the signal and increase of penetration of light in the cortex is better in the child population than in the adult population 5 due to their thinner hair, skin and skull.…”

Section: Introductionmentioning

confidence: 99%

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Espectroscopia de luz próxima ao infravermelho e processamento sensorial auditivo em lactentes

2016

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Purpose: to systematically review, through the search in the Medline and Lilacs database, the use of near-infrared spectroscopy (NIRS) as a tool to evaluate the auditory function at the cortical level in infants. Methods: integrative review based on the criteria established by the Cochrane Handbook including the definition of the guiding question (theme to be researched), definition of the database to locate the articles, and selection and critical analysis of the articles. The bibliographic search was performed from September to December 2014. The inclusion criteria were: articles published in English, Portuguese and Spanish related to the child population (infants aged from 0 to 24 months) and type of study (cohort, case-control, cross-sectional).Results: 1674 articles were identified and 12 met the inclusion criteria of this study. In all articles, the auditory stimulation was used to measure brain hemodynamic changes, but in different areas of interest of the brain. They were grouped into three categories according to the type of stimulus: only vocal sounds, vocal sounds and other auditory stimuli and non-vocal sounds. Conclusion: NIRS is an effective tool for the evaluation of the auditory function at the cortical level in the child population. Keywords: Spectroscopy, Near-Infrared; Hemodynamics; Auditory Perception; Hearing; Central Nervous System RESUMO Objetivo: revisar sistematicamente, por meio de busca nas plataformas Medline e Lilacs o uso da espectroscopia de luz próxima ao infravermelho (NIRS) como instrumento para a avaliação da audição a nível cortical em lactentes. Métodos: foi realizada uma revisão integrativa baseada nos critérios estabelecidos pela Cochrane Handbook, passando pelas etapas de definição da questão norteadora (o tema a ser pesquisado), definição das bases de dados para localização dos estudos, seleção e análise crítica dos artigos. A pesquisa bibliográfica foi realizada no período de setembro a dezembro de 2014. Os critérios de inclusão utilizados foram: artigos publicados nos idiomas inglês, português e espanhol, com a população infantil (bebês de 0 a 24 meses) e tipo de estudo (coorte, caso controle, transversal). Resultados: foram identificados 1674 artigos e 12 atenderam os critérios de inclusão deste estudo. Todos os artigos utilizaram o estímulo auditivo para medir alterações na hemodinâmica cerebral, porém com áreas cerebrais de interesse diferentes. E foram agrupados em três categorias quanto ao tipo de estímulo: apenas sons vocais, sons vocais e outros estímulos auditivos e sons não vocais. Conclusão: a NIRS é um instrumento eficaz para investigação da audição a nível cortical na população infantil.

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Neuroimaging with near-infrared spectroscopy demonstrates speech-evoked activity in the auditory cortex of deaf children following cochlear implantation

Cited by 104 publications

References 59 publications

Adaptive benefit of cross-modal plasticity following cochlear implantation in deaf adults

Adaptive benefit of cross-modal plasticity following cochlear implantation in deaf adults

Cortical cross-modal plasticity following deafness measured using functional near-infrared spectroscopy

Espectroscopia de luz próxima ao infravermelho e processamento sensorial auditivo em lactentes

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