Neuroimaging with PET/MR: moving beyond 3 T in preclinical systems, when for clinical practice?

Arachchige, Arosh S. Perera Molligoda

doi:10.1007/s40336-023-00572-6

Cited by 4 publications

(2 citation statements)

References 23 publications

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“…Traditionally, neurosurgery has relied upon lower field strength MRI machines, typically operating at 1.5 or 3 Tesla. While these systems have been instrumental in guiding surgical interventions and aiding in preoperative planning, they often fall short in providing the level of detail required for complex neurosurgical cases [2,3]. The limitations of lower field strength MRI, such as reduced spatial resolution and limited contrast, have posed challenges in accurately delineating critical structures, identifying subtle abnormalities, and characterizing lesions, ultimately affecting the quality and safety of neurosurgical procedures [5,6].…”

Section: Introductionmentioning

confidence: 99%

“…The delicate and intricate nature of the human brain necessitates tools and techniques that allow for precise diagnosis, treatment planning, and surgical intervention. Among the many innovations that have revolutionized the field, one technology has emerged as a promising game-changer: the 7-Tesla Magnetic Resonance Imaging (7T MRI) scanner, which also received US FDA approval for clinical use in 2017 [1,2,3]. The introduction of 7T MRI represents a pivotal moment in the history of neurosurgery.…”

Section: Introductionmentioning

confidence: 99%

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A Systematic Review evaluating the role of the 7 T MRI in Neurosurgery: Unveiling Trends in the Literature So Far after Clinical Approval in 2017

Perera Molligoda Arachchige

2023

Preprint

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Aims(1) To assess the impact of 7-Tesla Magnetic Resonance Imaging (7T MRI) on neurosurgery, focusing on its applications in diagnosis, treatment planning, and post-operative assessment. (2) To systematically analyze and identify patterns and trends in the existing literature related to the utilization of 7T MRI in neurosurgical contexts.MethodsSystematic search of PubMed for studies published between January 1, 2017, and December 31, 2021, using MeSH terms related to 7T MRI and neurosurgery. Inclusion criteria: Studies involving patients of all ages, meta-analyses, systematic reviews, and original research. Exclusion criteria: Pre-prints, studies with insufficient data eg: case reports, letters, etc., non-English publications, and studies involving animal subjects. Data synthesis involved standardized extraction forms, and a narrative synthesis was performed.ResultsIdentified 83 records from PubMed, screened for inclusion criteria, resulting in 48 studies included in the systematic review. Most common neurosurgical procedures using 7T MRI: endoscopic neurosurgery, resective epilepsy surgery, and deep brain stimulation surgery. Commonly treated pathologies: cerebrovascular diseases, epilepsy, pituitary adenoma, and gliomas. USA, Netherlands, and Germany had the highest absolute number of publications, but the Netherlands showed the highest research productivity per 7T MRI available. A decline in research output in 2018 followed by an increase in subsequent years. Could not conduct a meta-analysis due to insufficient studies for each pathology.Conclusions7T MRI holds great potential in improving the characterization and understanding of various neurological and psychiatric conditions. Superiority of 7T MRI over lower field strengths demonstrated in terms of image quality, lesion detection, and tissue characterization. Applications in epilepsy, pituitary adenoma, Parkinson’s disease, cerebrovascular diseases, trigeminal neuralgia, traumatic head injury, multiple sclerosis, glioma, and psychiatric disorders. Limitations include database selection, research productivity metrics, and study inclusion criteria. Findings suggest the need for accelerated global distribution of 7T MR systems and increased training for radiologists to ensure safe and effective integration into routine clinical practice.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Systematic Review evaluating the role of the 7 T MRI in Neurosurgery: Unveiling Trends in the Literature So Far after Clinical Approval in 2017

Perera Molligoda Arachchige

2023

Preprint

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Empowering radiology: the transformative role of ChatGPT

Perera Molligoda Arachchige

2023

Clinical Radiology

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Evaluating the role of 7-Tesla magnetic resonance imaging in neurosurgery: Trends in literature since clinical approval

Perera Molligoda Arachchige,

Meuli,

Centini

et al. 2024

World J Radiol

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BACKGROUND After approval for clinical use in 2017, early investigations of ultra-high-field abdominal magnetic resonance imaging (MRI) have demonstrated its feasibility as well as diagnostic capabilities in neuroimaging. However, there are no to few systematic reviews covering the entirety of its neurosurgical applications as well as the trends in the literature with regard to the aforementioned application. AIM To assess the impact of 7-Tesla MRI (7T MRI) on neurosurgery, focusing on its applications in diagnosis, treatment planning, and postoperative assessment, and to systematically analyze and identify patterns and trends in the existing literature related to the utilization of 7T MRI in neurosurgical contexts. METHODS A systematic search of PubMed was conducted for studies published between January 1, 2017, and December 31, 2023, using MeSH terms related to 7T MRI and neurosurgery. The inclusion criteria were: Studies involving patients of all ages, meta-analyses, systematic reviews, and original research. The exclusion criteria were: Pre-prints, studies with insufficient data (e.g. , case reports and letters), non-English publications, and studies involving animal subjects. Data synthesis involved standardized extraction forms, and a narrative synthesis was performed. RESULTS We identified 219 records from PubMed within our defined period, with no duplicates or exclusions before screening. After screening, 125 articles were excluded for not meeting inclusion criteria, leaving 94 reports. Of these, 2 were irrelevant to neurosurgery and 7 were animal studies, resulting in 85 studies included in our systematic review. Data were categorized by neurosurgical procedures and diseases treated using 7T MRI. We also analyzed publications by country and the number of 7T MRI facilities per country was also presented. Experimental studies were classified into comparison and non-comparison studies based on whether 7T MRI was compared to lower field strengths. CONCLUSION 7T MRI holds great potential in improving the characterization and understanding of various neurological and psychiatric conditions that may be neurosurgically treated. These include epilepsy, pituitary adenoma, Parkinson's disease, cerebrovascular diseases, trigeminal neuralgia, traumatic head injury, multiple sclerosis, glioma, and psychiatric disorders. Superiority of 7T MRI over lower field strengths was demonstrated in terms of image quality, lesion detection, and tissue characterization. Findings suggest the need for accelerated global distribution of 7T magnetic resonance systems and increased training for radiologists to ensure safe and effective integration into routine clinical practice.

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Neuroimaging with PET/MR: moving beyond 3 T in preclinical systems, when for clinical practice?

Cited by 4 publications

References 23 publications

A Systematic Review evaluating the role of the 7 T MRI in Neurosurgery: Unveiling Trends in the Literature So Far after Clinical Approval in 2017

A Systematic Review evaluating the role of the 7 T MRI in Neurosurgery: Unveiling Trends in the Literature So Far after Clinical Approval in 2017

Empowering radiology: the transformative role of ChatGPT

Evaluating the role of 7-Tesla magnetic resonance imaging in neurosurgery: Trends in literature since clinical approval

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