2021
DOI: 10.1212/cpj.0000000000001014
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Neuroinflammation Associated With Tumor Necrosis Factor-α Inhibitor Exposure

Abstract: Objective:To identify the frequency and clinical spectrum of neuroinflammation associated with exposure to tumor necrosis factor alpha inhibitors (TNFi).Methods:We performed a single-system retrospective cohort study. Adults in the Yale New Haven Health System with documented use of any FDA-approved TNFi between 2007-2017 were identified via automated review of the electronic medical record. Those who also had brain MRIs were identified and categorized as either TNFi exposed or unexposed. Individuals with MRI … Show more

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