“…There are no randomised controlled trials in this area but uncontrolled case series report (10,11,12,13) indicate a response in delirium symptoms similar to haloperidol with less EPS and sedation -Olanzapine (5-10mg) and Risperidone (1.5-4mg). However, as the post-traumatic brain is sensitive, care must still be taken in their use as side effects do occur and may include neuroleptic malignant syndrome (14). Behavioural disturbance may restrict their use until IM preparations are available Olanzapine IM is expected shortly.…”