Psychosocial interventions in five people, who presented with uncooperative and difficult behaviour at mealtimes and during assistance with self-care tasks, are described. In four cases, a single case experimental design was used. The results are discussed in the context of 'rementia' and a broadly defined functional analytic perspective to assessment and intervention. In contrast to the standard neurogenicdisease paradigm, a person-centred holistic model of dementia is proposed for the understanding and amelioration of distress in people with dementia who are seen as difficult or 'challenging'.