1961
DOI: 10.1212/wnl.11.7.553
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Neurologic sequelae of Japanese B encephalitis

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Cited by 50 publications
(22 citation statements)
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“…The incidence of Parkinsonism in other forms of encephalitis is far less common, although it has been documented after western equine (Mulder et al, 1951). Coxsackie B (Walters, 1960), Japanese B (Richter and Shimojyo, 1961), measles (Meyer, 1943), and possibly polio virus encephalitis (Duvoisin and Yahr, 1965). The mechanism of production of the Parkinsonism is unclear, but in the acute cases it is presumably caused by direct damage by the virus to the substantia nigra or the striatum.…”
Section: Discussionmentioning
confidence: 99%
“…The incidence of Parkinsonism in other forms of encephalitis is far less common, although it has been documented after western equine (Mulder et al, 1951). Coxsackie B (Walters, 1960), Japanese B (Richter and Shimojyo, 1961), measles (Meyer, 1943), and possibly polio virus encephalitis (Duvoisin and Yahr, 1965). The mechanism of production of the Parkinsonism is unclear, but in the acute cases it is presumably caused by direct damage by the virus to the substantia nigra or the striatum.…”
Section: Discussionmentioning
confidence: 99%
“…Mild infections produce a flulike illness that resolves within 5 to 7 days (Case 6-2). More serious infections are associated with meningoencephalitis or other CNS manifestations (Richter and Shimojyo, 1961). Patients initially present with fever, headache, and vomiting and progress rapidly.…”
Section: Clinical Manifestationsmentioning
confidence: 99%
“…The mortality rate in most outbreaks is less than 10% but in children can exceed 30%. Neurological sequelae occur in up to 30% of patients who survive severe infection (Richter and Shimojyo, 1961). In one study of survivors of severe Japanese encephalitis, neurological deficits were common and included quadriplegia (60%), hemiplegia (12%), muscle wasting (25%), and seizures (50%) (Kalita et al, 2003).…”
Section: Treatmentmentioning
confidence: 99%
“…2 About 30% of survivors have frank motor deficits including a mixture of upper and lower motor neuron weakness, and cerebellar and extra pyramidal signs, fixed flexion deformities of the arms, and hyperextension of the legs with "equine feet" are common. 75 Twenty percent of patients have severe cognitive and language impairment (most with motor impairment also), and 20% have further convulsions. 51,76 A higher rate of sequelae is reported for children than adults.…”
Section: Outcomementioning
confidence: 99%