Neurological and autoimmune disorders after vaccination against pandemic influenza A (H1N1) with a monovalent adjuvanted vaccine: population based cohort study in Stockholm, Sweden

Abstract

Objective To examine the risk of neurological and autoimmune disorders of special interest in people vaccinated against pandemic influenza A (H1N1) with Pandemrix (GlaxoSmithKline, Middlesex, UK) compared with unvaccinated people over 8-10 months.

Environmental Factors and Type 1 Diabetes Mellitus in Pediatric Age Group

“…Similar results have been reported in a retrospective cohort study in active components of US Military between 2002-2008 [153]. Another retrospective cohort study in Sweden examining the risk of autoimmune and neurological disorders in people vaccinated against pandemic influenza A demonstrated no changes in the frequency of several autoimmune diseases, including T1DM [154].…”

International collaboration to assess the risk of Guillain Barré Syndrome following Influenza A (H1N1) 2009 monovalent vaccines

“…This risk is consistent with the level of risk reported by others. Estimates from single-country studies ranged from 1.05 to 4.70, the majority of which reported statistically significant increased risk [23][24][25][26][27][28][29][30][31][32]. Estimates were lower in studies of adjuvanted vaccines (1.05-3.04) [25,31] than in non-adjuvanted vaccines (1.57-4.70) [26][27][28][29][30]32].…”

New Quality-Control Investigations on Vaccines: Micro- and Nanocontamination

“…The investigations revealed that some particles are embedded in a biological substrate, probably proteins, endo-toxins and residues of bacteria. As soon as a particle comes in contact with proteic fluids, a nano-bio-interaction [6] occurs and a "protein corona" is formed [7][8][9][10]. The nano-bio-interaction generates a biggersized compound that is not biodegradable and can induce adverse effects, since it is not recognized as self by the body.…”

“…For instance, the diphtheria-tetanus-pertussis (DTaP) vaccine was linked to cases of sudden infant death syndrome (SIDS) [3]; measles-mumps-rubella vaccine with autism [4,5]; multiple immunizations with immune disorders [6]; hepatitis B vaccines with multiple sclerosis, etc.…”