Neurological and electroneurography findings in patients with systemic sclerosis and symptoms of neuropathic pain in extremities

Ostojić, Predrag; Knezevic-Apostolski, Sladjana; Djurovic, Nada; Stojic, B; Jankovic, Katarina; Bartolovic, D.

doi:10.1007/s13760-018-1048-z

Cited by 3 publications

(1 citation statement)

References 22 publications

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“…[ 25 ] The importance of neuropathic pain in SSc has been recently considered. [ 27 , 28 , 29 ] Among the patients with SSc and pain examined in the present investigation, in 2 patients with joint pain and in 1 patient with pain due to digital ulcers, some clinical features were present which could suggest a component of neuropathic pain: those patients reported a “burning” quality of spontaneous pain associated with paresthesias in some body regions, and in the same regions, the phenomenon of hyperalgesia was observed at sensory examination. No patient reported previous herpes zoster virus infection.…”

Section: Resultsmentioning

confidence: 68%

The emerging challenge of pain in systemic sclerosis: Similarity to the pain experience reported by Sjőgren’s syndrome patients

Luca

Maresca

Orlandi

et al. 2021

Rheumatology and Immunology Research

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In order to evaluate the importance of pain in systemic sclerosis (SSc), the characteristics of pain reported by patients with SSc were analyzed and compared with the characteristics of pain reported by patients with primary Sjőgren’s syndrome (pSS). Pain was reported by 56 patients (80%) in a group of 70 patients with SSc and by 25 patients (78%) in a group of 32 patients with pSS. Pain severity was assessed by the Pain Rating Index (PRI) and the Present Pain Intensity (PPI) of the McGill Pain Questionnaire (MPQ) and by values obtained by a visual analog scale (VAS) indicating the intensity of pain felt in the moment of the examination and the intensity of pain felt in the week preceding the moment of the examination. No significant difference was detected in the comparison of mean values of pain indices between patients with SSc and patients with pSS and in the comparison among subgroups of patients with SSc. The data indicate that pain is a frequent and important cause of suffering in SSc as in other chronic diseases. The association of different methods may be especially useful to obtain a careful evaluation of pain in clinical research.

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Section: Resultsmentioning

confidence: 68%

The emerging challenge of pain in systemic sclerosis: Similarity to the pain experience reported by Sjőgren’s syndrome patients

Luca

Maresca

Orlandi

et al. 2021

Rheumatology and Immunology Research

View full text Add to dashboard Cite

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Biomarkers reflecting the pathogenesis, clinical manifestations, and guide therapeutic approach in systemic sclerosis: a narrative review

Bazsó,

Szodoray,

Shoenfeld

et al. 2024

Clin Rheumatol

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Systemic sclerosis (SSc) is a progressive autoimmune disorder that mainly affects the skin. There are other clinical manifestations as renal, pulmonary, cardiovascular, and gastrointestinal tract involvements. Based on the skin involvement there are two subtypes of SSc, as limited cutaneous SSc (lSSc) which involves the acral part of the body and diffuse cutaneous SSc (dSSc) resulting in significant skin thickening of the body. Despite of the extensive research the pathomechanism is not fully clarified, how Ssc develops, moreover identifying biomarkers to predict the clinical outcome and prognosis still remains challenging. Circulating biomarkers can be crucial to define the diagnosis, to predict the prognosis and monitor the clinical course. However, only some patients are responsive to the therapy in SSc, and there is a need to reach the ideal therapy for any individual to prevent or slow down the progression in early stages of the disease. In this narrative review, our purpose was to summarize the potential biomarkers in Ssc, describe their role in the diagnosis, pathomechanism, clinical course, organ manifestations, as well as the response to the therapy. Biomarkers assessment aids in the evaluation of disease progression, and disease outcome.

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Prevalence of painful diabetic peripheral neuropathy in type 2 diabetes mellitus and diabetic peripheral neuropathy: A nationwide cross-sectional study in mainland China

Li¹,

Wang²,

Ji³

et al. 2023

Diabetes Research and Clinical Practice

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Neurological and electroneurography findings in patients with systemic sclerosis and symptoms of neuropathic pain in extremities

Cited by 3 publications

References 22 publications

The emerging challenge of pain in systemic sclerosis: Similarity to the pain experience reported by Sjőgren’s syndrome patients

The emerging challenge of pain in systemic sclerosis: Similarity to the pain experience reported by Sjőgren’s syndrome patients

Biomarkers reflecting the pathogenesis, clinical manifestations, and guide therapeutic approach in systemic sclerosis: a narrative review

Prevalence of painful diabetic peripheral neuropathy in type 2 diabetes mellitus and diabetic peripheral neuropathy: A nationwide cross-sectional study in mainland China

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