“…Of 17 studies reporting psychiatric symptoms in adults with PKU, the 10 reporting prevalence of inattention, hyperactivity, anxiety, or depression were included in the MA (Anjema et al, 2011; Brumm et al, 2004;Campistol, González, Gutiérrez, & Vilaseca, 2012;Fisch et al, 1995;González et al, 2011;Kalkanoğlu et al, 2005;Koch et al, 2002;Pietz, Fatkenheuer, Armbruster, Esser, & Schmidt, 1997;Ris et al, 1997;Schuett et al, 1985). Of 19 studies reporting neurologic symptoms, the 10 reporting prevalence of both epilepsy/seizures and tremors were included in the MA (Campistol et al, 2012;Crowley, Koch, Fishler, Wenz, & Ireland, 1990;González et al, 2011;Leuzzi, Bianchi, Tosetti, Carducci, & Antonozzi, 2000;Leuzzi, Trasimeni, Gualdi, & Antonozzi, 1995;McDonnell, Esmonde, Hadden, & Morrow, 1998;Pfaendner et al, 2005;Pitt & Danks, 1991;Schuett et al, 1985;Thompson et al, 1993).…”