Neurological complications in Kawasaki disease

Terasawa, Kenjiro; Ichinose, Eisei; Matsuishi, Toyojiro; Kato, Hirohisa

doi:10.1016/s0387-7604(83)80041-2

Cited by 94 publications

(58 citation statements)

References 7 publications

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“…Neurologic complications in KD have been shown to affect 1.1% of children in a Japanese cohort of 450 children with KD [12]. Aseptic meningitis is the most common, accounting for 5% of all neurologic complications [13].…”

Section: Discussionmentioning

confidence: 99%

Atypical Kawasaki Disease in 2-Months Old Infant Presenting with Aseptic Meningitis

Salameh¹,

Omer²,

Hamad³

et al. 2017

Pediatr Ther

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The diagnosis of incomplete or atypical Kawasaki disease (KD) is challenging. Children presenting with febrile illnesses may have few of the classical diagnostic criteria, yet develop clinical, laboratory and echocardiographic findings compatible with the condition.Early recognition and prompt treatment of KD is essential for better outcomes. This is particularly the case for infants who are at a greater risk of developing complications such as coronary artery aneurysms. This may be partly attributed to late diagnosis or initiation of therapy.This report discusses the case of a febrile infant with atypical Kawasaki disease presenting with aseptic meningitis and coronary artery aneurysm.The case highlights the importance of considering atypical Kawasaki disease in any infant with prolonged fever (more than seven days), following exclusion of infectious causes and in the absence of classical diagnostic criteria.

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Section: Discussionmentioning

confidence: 99%

Atypical Kawasaki Disease in 2-Months Old Infant Presenting with Aseptic Meningitis

Salameh¹,

Omer²,

Hamad³

et al. 2017

Pediatr Ther

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“…Ischemia is probably associated with vasculitic inflammation of attendant arteries supplying facial nerve. Also immunologic mechanisms can probably contribute to the occurrence of facial nerve palsy (4,9,13,15,26) . Facial nerve palsy associated with KD was noted at intervals ranging from 2 to 37 days after onset of illness.…”

Section: Discussionmentioning

confidence: 99%

“…Neurologic manifestations have been reported to occur in %1.1 to %30 of cases of KD. These manifestations include irritability, lethargy, aseptic meningitis, ataxia, seizures, focal encephalopathy, cranial nerve palsies, cerebral infarction, subdural effusion, senserineural hearing loss and transient hemiplegia (4)(5)(6)(7)(8)(9)(10) . Facial nerve palsy (FNP) is among the rarest neurologic complications that have now been reported in literature in only 37 cases.…”

Section: Introductionmentioning

confidence: 99%

Kawasakı Dısease Complıcated By Facıal Nerve Palsy: A Case Report And Revıew Of Lıterature

Karbuz¹,

Kocabaş²,

Özdemir³

et al. 2016

BUCH

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Facial nerve palsy is a rare neurologic manifestation of Kawasaki disease. There are several mechanisms in the pathogenesis of facial nerve palsy. It is usually transient and lasts for 1 to 90 days. Under normal conditions it resolves spontaneously and completely. Presence of facial paralysis indicates an increased risk of coronary artery aneurism. In this report, a ten month-old girl with prolonged fever, aseptic meningitis and facial palsy who later diagnosed as Kawasaki disease was described and also the clinical features of 37 cases in the literature were reviewed.Key words: Kawasaki disease, facial nerve palsy, children ÖZFasiyal sinir paralizisi, Kawasaki hastalığının ender görülen nörolojik bir bulgusudur. Fasiyal sinir paralizisinin oluşumu ile ilgili birkaç mekanizmadan bahsedilmektedir. Genellikle geçici olup, 1-90 gün sürer. Normal şartlar altında kendiliğinden tamamen iyileşir. Fasiyal sinir paralizisi saptanması halinde, artmış koroner arter anevrizma riskinin olduğundan bahsedilir. Bu makalede, uzamış ateş, aseptic menenjit ve fasiyal paralizisi olan ve sonradan Kawasaki hastalığı tanısı konan 10 aylık kız çocuğu, literaturde sunulan olgular ile birlikte derlenerek bildirilmiştir. Anahtar kelimeler: Kawasaki hastalığı, fasial sinir paralizisi, çocukAlındığı tarih:

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“…The reported incidence of neurological complications in KD is approximately 1.1% 13) ; while an uncommon occurrence, ex tracerebral fluid collection has been previously reported 8,14,15) and is generally detected following computed tomography (CT) or MRI of the brain. However, the value of lumbar puncture is un clear, given that some of the patients did not undergo lumbar puncture, and others who did undergo lumbar puncture had normal CSF findings.…”

Section: Discussionmentioning

confidence: 99%

Incomplete Kawasaki Disease in a 5-Month-Old Girl Associated with Cerebrospinal Fluid Pleocytosis and Epidural Fluid Collection

Kim

Lee

Han

2015

Pediatr Infect Vaccine

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Cases of incomplete Kawasaki disease (KD), wherein the patient does not fulfill the full diagnostic criteria for KD, are often detected in infants younger than 6 months of age. The clinical manifestations in infants with incomplete KD may resemble other infectious diseases, including meningitis. For this reason, clinicians may have difficulty differentiating incomplete KD from other infectious diseases in this population. Various neurological features are associated with KD, including aseptic meningitis, subdural effusion, facial nerve palsy, cerebral infarction, encephalopathy, and reversible corpus callosum splenial lesions on magnetic resonance imaging. We report a case of a 5-monthold girl with incomplete KD, associated with cerebrospinal fluid pleocytosis and an epidural fluid collection. Echocardiography indicated dilatation of the main coronary arteries. The girl made a complete recovery, with resolution of both the epidural fluid collection and coronary artery aneurysms. In this case, the child is well, and showed normal developmental milestones at the 7-month follow-up.

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Neurological complications in Kawasaki disease

Cited by 94 publications

References 7 publications

Atypical Kawasaki Disease in 2-Months Old Infant Presenting with Aseptic Meningitis

Atypical Kawasaki Disease in 2-Months Old Infant Presenting with Aseptic Meningitis

Kawasakı Dısease Complıcated By Facıal Nerve Palsy: A Case Report And Revıew Of Lıterature

Incomplete Kawasaki Disease in a 5-Month-Old Girl Associated with Cerebrospinal Fluid Pleocytosis and Epidural Fluid Collection

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