Neurological Complications of Hypothyroidism

Türker, Hande; Turker, Cuneyt; Cengiz, Nilgün

doi:10.5772/31397

Cited by 6 publications

(5 citation statements)

References 65 publications

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“…In human infants, congenital hypothyroidism can also cause a range of other neuromuscular sequelae, including abnormal muscle tone, severe muscle weakness, ataxia and motor incoordination. 29,30 Although the exact pathogenesis of these neuromuscular signs in our cat is not clear, marked improvement was evident with successful thyroid hormone replacement therapy.…”

Section: Discussionmentioning

confidence: 79%

Primary goitrous hypothyroidism in a young adult domestic longhair cat: diagnosis and treatment monitoring

Peterson

2015

Journal of Feline Medicine and Surgery Open Reports

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Case summaryPrimary goitrous hypothyroidism was diagnosed in a 12-month-old cat examined because of small stature, mental dullness, severe lethargy, generalized weakness and gait abnormalities. Radiographs of the long bones and spine revealed delayed epiphyseal ossification and epiphyseal dysgenesis. Diagnosis of primary hypothyroidism was confirmed by low serum concentrations of total and free thyroxine (T4) with high thyroid-stimulating hormone (TSH) concentrations. Thyroid scintigraphy revealed severe enlargement of both thyroid lobes, as evidenced by a seven-fold increase in calculated thyroid volume above the reference interval. In addition, this bilateral goiter had an extremely high radionuclide uptake, about 10-fold higher than the normal feline thyroid gland. Treatment with twice-daily levothyroxine (L-T4), administered on an empty stomach, resulted in increased alertness, playfulness, strength and improvement in gait, as well as an increase in body length and weight. L-T4 replacement also led to normalization of serum thyroid hormone and TSH concentrations, and complete resolution of goiter.Relevance and novel informationSpontaneous hypothyroidism is rarely reported in cats, with congenital hypothyroidism in kittens diagnosed most frequently. Despite the fact that this cat was a young adult, it likely had a form of congenital hypothyroidism caused by dyshormonogenesis (defect in thyroid hormone synthesis) that led to compensatory development of goiter. In hypothyroid cats, treatment with L-T4 is best given twice daily on an empty stomach to ensure adequate absorption. Normalization of serum TSH and shrinkage of goiter, as well as improvement in clinical signs, is the goal of treatment for cats with goitrous hypothyroidism.

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Section: Discussionmentioning

confidence: 79%

Primary goitrous hypothyroidism in a young adult domestic longhair cat: diagnosis and treatment monitoring

Peterson

2015

Journal of Feline Medicine and Surgery Open Reports

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“…81. madde ile hâkimlerin azlolunamayacağı hüküm altına alınmıĢ ve hâkimlerle ilgili yükselme, yer değiĢtirme, emeklilik ve görevden el çektirme gibi iĢlemlerin özel bir kanun ile düzenleneceği öngörülmüĢtür. 37 hal" denilen kimseler bulunmakta idi. 41 Kanun-ı Esasi"de 82. madde ile getirilen hüküm ile yargının aleniliği anayasal güvence altına alınmıĢtır.…”

Section: Hukukun Genel ġLkelerġnġn Kanun-i Esasġdekġ Görünümlerġunclassified

Hukukun Genel İlkeleri Bağlamında Kanun-i Esasi deki Yargılamaya İlişkin Hükümlerin Değerlendirilmesi

Ülker¹

2013

SUHFD

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“…7 Unmanaged and untreated thyroid disorders leads to life threatening and serious complications like cardiovascular diseases, infertility, complications during pregnancy neurological complications myxoedema coma For overall complications. [8][9][10][11] Knowing about risk factors, symptoms and complications can help to avoid complications and manage symptoms. Misconceptions always result in psychological stress and increase unnecessary anxiety in patients, correcting the misconceptions is as equally important as providing patient education, it directly contributes to patients psychological wellbeing.…”

Section: Introductionmentioning

confidence: 99%

Assessment of knowledge, awareness, practices and misconceptions among hypothyroid and hyperthyroid patients

Savitha,

Kata,

Chinthagani

et al. 2023

Int J Res Med Sci

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Background: In chronic illness there is a greater need for patient education to manage their symptoms, prevent complications, and have better therapeutic outcome and increase quality of life. Among chronic illnesses thyroid disorders are more common in the world. Our study aimed to assess knowledge, awareness, practices and misconceptions in thyroid patients in order to estimate the need of patient education and also counsel the patients for the same using counselling aids. Methods: A descriptive cross sectional study was conducted among 300 subjects in a secondary care hospital for a period of 6 months (February 2017- July 2017). The interviews were conducted in semi private areas in the hospital after taking informed consent by using a structured questionnaire which has been established for its validity and reliability. The results were calculated using descriptive statistical methods (frequency, percentage and mean). Results: Among the participants 23.33% were co-morbidities, majority of patients (83%) do not have family history. Only 32% of the participants have good knowledge, 52.66% have average knowledge and 15.33% patients have poor knowledge about symptoms. Though the knowledge on the dietary factors is considerable in participants, 31.95% of hypothyroid, 58.82% of hyperthyroid patients followed inappropriate dietary habits. 86.3% believed that patients with thyroid disorders need to take medications for their lifetime. Conclusions: The results conclude the need for patient education in thyroid disorders and also a need for clinical pharmacists in hospital setup to fill the gap between physician and patient to provide patient education and clarify misconceptions.

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Neurological Complications of Hypothyroidism

Cited by 6 publications

References 65 publications

Primary goitrous hypothyroidism in a young adult domestic longhair cat: diagnosis and treatment monitoring

Primary goitrous hypothyroidism in a young adult domestic longhair cat: diagnosis and treatment monitoring

Hukukun Genel İlkeleri Bağlamında Kanun-i Esasi deki Yargılamaya İlişkin Hükümlerin Değerlendirilmesi

Assessment of knowledge, awareness, practices and misconceptions among hypothyroid and hyperthyroid patients

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