Neurological Considerations for “Nerve-Sparing” Cosmetic Genital Surgeries Performed on Children with XX Chromosomes Diagnosed with 21-Hydroxylase Congenital Adrenal Hyperplasia and Clitoromegaly

Purpose of ReviewTo summarize the literature on neurologic care for transgender and gender-diverse (TGD) people and provide implications for clinical practice. Recent FindingsThere are limited data on the frequency and management of neurologic conditions among TGD people. TGD people have a higher prevalence of various neurologic conditions compared with cisgender or general population cohorts, including migraine, subjective cognitive decline, sleep disturbances, functional disorders, and cerebrovascular disease. Gender-affirming hormone therapy interacts with commonly prescribed neurologic medications and increases stroke risk among transfeminine people. Sex hormones and sex chromosomes may play a role in neurodegeneration and disability progression in neuroimmunologic diseases. Clitoral reduction surgeries on intersex children can cause neurologic disability and sexual dysfunction in adulthood. Socioeconomic disparities among TGD people contribute to health care barriers. SummaryNeurologists should consider the unique experiences and health care needs of TGD people in their clinical practice and research protocols.

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Neurological Considerations for “Nerve-Sparing” Cosmetic Genital Surgeries Performed on Children with XX Chromosomes Diagnosed with 21-Hydroxylase Congenital Adrenal Hyperplasia and Clitoromegaly

Cited by 4 publications

References 58 publications

Neurological care for LGBT+ people

Neurological care for LGBT+ people

Countering the Health Disinformation Machine

Neurologic Care for Transgender and Gender-Diverse People

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