Neurological evaluation and intelligence testing in the child with operated congenital heart disease

Sharma, Rajesh; Choudhary, Shiv Kumar; Mohan, Marla Ram; Padma, MV; Jain, Suruchi; Bhardwaj, Madhu; Bhan, Anil; Kiran, Usha; Saxena, Nita; Venugopal, Panangipalli

doi:10.1016/s0003-4975(00)01397-7

Cited by 36 publications

(24 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Scores lower than expected on language tests were also found in survivors of staged palliation for hypoplastic left heart syndrome (Sharma et al, 2000). Similarly, language deficits were observed in children with transposition of the great arteries: 18.3% had reduced scores on expressive language tasks (all below 1 standard deviation) and 21.6% on receptive language tasks (18.3% below one standard deviation, 3.3% below 2 standard deviations) (Hövels-Gürich et al, 2002).…”

Section: Languagementioning

confidence: 78%

“…The median full scale IQ of children with hypoplastic left heart syndrome who underwent at least two stages of surgical palliation was found to be 88, indicating low average intelligence (Kern et al, 1998). When standardized testing was performed in 28 children with hypoplastic left heart syndrome who had undergone palliative surgery (mean age at testing 8.6 years), the results revealed lower performance IQ scores than verbal IQ scores, borderline low range scores for full scale IQ in 35.7% of the survivors, and 17.8% IQ scores below 70 were reported (Sharma et al, 2000). A first study on 38 children with various congenital heart defects who were assessed 22 months to 6 years after open-heart surgery reported normal intellectual capacities (Dickinson & Sambrooks, 1979).…”

Section: Intellectual Performancementioning

confidence: 99%

See 1 more Smart Citation

Neurocognitive Consequences of Surgically Corrected Congenital Heart Defects: A Review

et al. 2006

View full text Add to dashboard Cite

With advances in surgical procedures, neuropsychological assessment after congenital heart defects and pre, peri- and/or postoperative predictors of adverse outcome has become an important focus in research. We aim to summarize neuropsychological sequelae associated with different types of congenital heart defects, critically review the methodology used in more than 20 empirical studies that were retrieved from biomedical electronic search engines, and identify possible directions for future research. Despite the lack of adequate control groups and long-term studies, there seem to be some cognitive deficits. The largest group of children with isolated congenital heart defects present with normal intellectual capacities. However, they tend to show language deficits and motor dysfunction. Although performances on memory tasks are good, unambiguous conclusions concerning their attentional and executive functioning are still lacking. Serious behavioral problems are not an issue. In addition to a detailed description of the (neuro) psychological consequences of pediatric cardiac surgery, an overview of the predictors of the cognitive defects is provided.

show abstract

Section: Languagementioning

confidence: 78%

Section: Intellectual Performancementioning

confidence: 99%

Neurocognitive Consequences of Surgically Corrected Congenital Heart Defects: A Review

et al. 2006

View full text Add to dashboard Cite

show abstract

“…[1][2][3][4][5][6][7][8][9] Although genetic attributes as well as multiple preoperative, intraoperative, and postoperative factors are likely contributors to cognitive outcome in these children, particular attention has focused on the potential for cerebral injury during cardiopulmonary bypass (CPB). 4,10 -13 The etiologic factors contributing to injury during CPB are incompletely defined but likely include cerebral hypoperfusion, cerebral embolic injury, and a global inflammatory response.…”

mentioning

confidence: 99%

Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children

2003

View full text Add to dashboard Cite

Background-Changes in neurocognitive function after cardiopulmonary bypass (CPB) are difficult to assess in children with congenital cardiovascular malformations in part because identification of a suitable control group of children is difficult. Methods and Results-We evaluated neurocognitive function in subjects aged 3 to 17 years both before and after surgical repair of an atrial septal defect (ASD). Eighteen subjects underwent testing within a median of 3 days (range, 1 to 27) before surgery and 5.8 months (range, 5.5 to 9) after surgery. The Differential Ability Scales was administered to subjects in a single testing session. All subjects were considered to be healthy, and they had no activity limitations. The mean General Conceptual Ability (GCA) scores (analogous to IQ) for the group were in the normal range before and after ASD repair. No significant difference was detected between the GCA scores before and after surgery. The GCA score was 90.8Ϯ18.6 before surgery and 93.1Ϯ16.3 after surgery. Conclusions-Use

show abstract

“…The cognitive development of these patients has therefore become a major focus of the effort to assess the quality of late outcomes after surgery for congenital heart disease early in life. [1][2][3][4][5][6][7] Patients with functional single-ventricle physiology might be at particular risk for neurodevelopmental delay, for a number of reasons. If there has not been a prenatal diagnosis, circulatory collapse may ensue after ductal closure.…”

mentioning

confidence: 99%

Neurodevelopmental Outcomes in Children After the Fontan Operation

et al. 2001

View full text Add to dashboard Cite

Background-Previous studies of patients after the Fontan operation have reported IQ scores lower than population norms.In the past decade, changes have occurred both in surgical methods used and in the patient population undergoing Fontan palliation. The present study examined the impact of these changes on neurodevelopmental outcomes after Fontan. Methods and Results-Neuropsychological tests were administered to 27 five-year-old children after Fontan. Mean age at repair was 2 years 4 months. The present sample was compared with an earlier Fontan group (EFG) of 133 patients who underwent surgery in the 1970s and 1980s. Mean age at repair for the EFG was 7 years 3 months. Compared with EFG, the present study sample was younger at Fontan (Pϭ0.0001) and more likely to have undergone a Norwood procedure (Pϭ0.02), a pre-Fontan bidirectional cavopulmonary anastomosis (PϽ0.001), and Fontan fenestration (Pϭ0.001).Although mean full-scale, verbal, and performance IQ scores were within 1 SD (15 points) of the population mean of 100 (93Ϯ16, 95Ϯ15, and 91Ϯ17, respectively), mean full-scale and performance IQ scores were significantly lower than this population mean (Pϭ0.03 and Pϭ0.01, respectively). Conclusions-Compared

show abstract

Neurological evaluation and intelligence testing in the child with operated congenital heart disease

Cited by 36 publications

References 23 publications

Neurocognitive Consequences of Surgically Corrected Congenital Heart Defects: A Review

Neurocognitive Consequences of Surgically Corrected Congenital Heart Defects: A Review

Cardiopulmonary Bypass to Repair an Atrial Septal Defect Does Not Affect Cognitive Function in Children

Neurodevelopmental Outcomes in Children After the Fontan Operation

Contact Info

Product

Resources

About