Neurologists׳ accuracy in predicting cognitive impairment in multiple sclerosis

Romero, Kristoffer; Shammi, Prathiba; Feinstein, Anthony

doi:10.1016/j.msard.2015.05.009

Cited by 49 publications

(47 citation statements)

References 27 publications

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“…This cognitive inefficiency and memory decline affects patient's employment, communication, disease management and quality of life in general 3 , regardless the stage or type of the disease 4 . Cognitive deficits may be undetected at consultation 5 .…”

Section: Introductionmentioning

confidence: 99%

Validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) in Greek population with multiple sclerosis

Polychroniadou

Bakirtzis

Langdon

et al. 2016

Multiple Sclerosis and Related Disorders

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Section: Introductionmentioning

confidence: 99%

Validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) in Greek population with multiple sclerosis

Polychroniadou

Bakirtzis

Langdon

et al. 2016

Multiple Sclerosis and Related Disorders

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“…The deterioration of cognitive performance, usually subtle at least during the first years of the disease course, is almost impossible to be diagnosed by routine neurological testing; therefore, special neuropsychological assessments are needed [ 18 ]. This deterioration may not be clinically evident at first and may be hidden by neuroplasticity, that is, the brain's capacity to reorganize its networks in order to keep on functioning despite tissue damage.…”

Section: Cognition In Msmentioning

confidence: 99%

Repetitive Transcranial Magnetic Stimulation, Cognition, and Multiple Sclerosis: An Overview

Nasios¹,

Messinis

Dardiotis

et al. 2018

Behavioural Neurology

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Multiple sclerosis (MS) affects cognition in the majority of patients. A major aspect of the disease is brain volume loss (BVL), present in all phases and types (relapsing and progressive) of the disease and linked to both motor and cognitive disabilities. Due to the lack of effective pharmacological treatments for cognition, cognitive rehabilitation and other nonpharmacological interventions such as repetitive transcranial magnetic stimulation (rTMS) have recently emerged and their potential role in functional connectivity is studied. With recently developed advanced neuroimaging and neurophysiological techniques, changes related to alterations of the brain's functional connectivity can be detected. In this overview, we focus on the brain's functional reorganization in MS, theoretical and practical aspects of rTMS utilization in humans, and its potential therapeutic role in treating cognitively impaired MS patients.

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“…Early symptoms of MS and its further course vary, depending on the location of the foci of demyelination [4,5,7,8].…”

Section: Clinical Presentation Of Multiple Sclerosismentioning

confidence: 99%

Physiotherapy in multiple sclerosis

Łuszczyńska¹,

Kuliński²

2015

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Introduction:Multiple sclerosis (MS) is a chronic, progressive, demyelinating disease of the central nervous system. 2.5 million people are affected by MS worldwide; in Poland, the number of patients is approximately 40,000. Patients with multiple sclerosis suffer from a number of symptoms associated with this disease. Aim of the research: To assess the effectiveness of physiotherapy in MS. Material and methods: The study enrolled 25 MS patients aged 27-72 years (including 16 females and 9 males), undergoing 6-week rehabilitation. They were examined twice: before and after rehabilitation. The study used two questionnaires created by the author. Evaluation of the clinical status and disease severity was based on the Kurtzke Expanded Disability Status Scales (EDSS), the Lawton Instrumental Activities of Daily Living (IADL) Scale, and the Multiple Sclerosis Impact Scale (MSIS-29). The results were analysed with Student's t-test and the chi-square (χ 2 ) test. Results: Statistical analysis showed significant (the level of significance was 0.05) progress in the functional status of the patients after physiotherapy, as evidenced by improved results with respect to the motor efficiency in the Kurtzke Expanded Disability Status Scale (EDSS), the functional assessment in the Lawton Instrumental Activities of Daily Living (IADL) Scale, and the influence of MS on patients' daily life in the Multiple Sclerosis Impact Scale (MSIS-29) seen in the majority of the patients, which confirms a positive impact of the therapy. Conclusions: In the study group, comprehensive rehabilitation had a beneficial influence on the improvement of functional status and the level of motor ability. Physiotherapy turned out to be an extremely effective form of symptomatic treatment of MS patients. Streszczenie Wprowadzenie: Stwardnienie rozsiane (SM) jest przewlekłą, postępującą, demielinizacyjną chorobą ośrodkowego układu nerwowego. Na SM choruje ok. 2,5 mln osób na świecie, w Polsce ta liczba wynosi ok. 40 tysięcy. Cel pracy: Ocena skuteczności fizjoterapii u pacjentów chorujących na SM. Materiał i metody: Badaniu poddano 25 osób chorych na SM w wieku 27-72 lat przebywających na 6-tygodniowym turnusie rehabilitacyjnym. Badanie przeprowadzono 2-krotnie, tj. przed rozpoczęciem usprawniania rehabilitacyjnego i po jego zakończeniu. W badaniach posłużono się dwiema autorskimi ankietami. Do oceny stanu klinicznego i zaawansowania choroby użyto ponadto Rozszerzonej skali niewydolności ruchowej Kurtzkego (EDSS), Skali oceny złożonych czynności życia codziennego -IADL (skala Lawtona) oraz Multiple Sclerosis Impact Scale (MSIS-29). Wyniki poddano analizie statystycznej, posłużono się przy tym testem t-Studenta dla dwóch prób zależnych oraz testem χ 2 . Wyniki: Analiza statystyczna wykazała znaczącą (na poziomie istotności 0,05) poprawę stanu funkcjonalnego pacjentów po zastosowaniu fizjoterapii. Może o tym świadczyć poprawa u większości badanych w zakresie: wydolności ruchowej w skali Kurtzkego, stanu funkcjonalnego ocenianego za pomocą skali IADL oraz wpł...

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Neurologists׳ accuracy in predicting cognitive impairment in multiple sclerosis

Cited by 49 publications

References 27 publications

Validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) in Greek population with multiple sclerosis

Validation of the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) in Greek population with multiple sclerosis

Repetitive Transcranial Magnetic Stimulation, Cognition, and Multiple Sclerosis: An Overview

Physiotherapy in multiple sclerosis

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