1998
DOI: 10.1111/j.1749-6632.1998.tb11228.x
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Neuromodulator Role of VIP in Recovery of Rat Behavior and Brain Neurotransmitters Level after Frontal Lobectomy

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Cited by 4 publications
(5 citation statements)
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“…8). Central nervous system VIP is antagonistic to dopamine and serotonin nervous activity (42,43). Both of these transmitters control food reward responses (44,45), and therefore VIP knockout mice may possess an elevated reward response, curtailing their intake and preventing weight increases.…”
Section: Discussionmentioning
confidence: 99%
“…8). Central nervous system VIP is antagonistic to dopamine and serotonin nervous activity (42,43). Both of these transmitters control food reward responses (44,45), and therefore VIP knockout mice may possess an elevated reward response, curtailing their intake and preventing weight increases.…”
Section: Discussionmentioning
confidence: 99%
“…The inoculation point chosen was safe for animals as rodents can tolerate frontal lobectomy and survive with behavioural and cognitive defective functions only (Karganov et al . ). 1 × 10 5 CFUs of Mycobacterium tuberculosis H37Rv were used for infection as per the earlier study (van Well et al .…”
Section: Discussionmentioning
confidence: 97%
“…The most recent study for generation of a mouse model of TBM emphasized the use of the intracranial route for the successful development of meningitis in mice (van Well et al 2007). The inoculation point chosen was safe for animals as rodents can tolerate frontal lobectomy and survive with behavioural and cognitive defective functions only (Karganov et al 1998). 1 9 10 5 CFUs of Mycobacterium tuberculosis H37Rv were used for infection as per the earlier study (van Well et al 2007) and generated a stable bacillary load in the brain for 12 weeks after infection.…”
Section: Discussionmentioning
confidence: 99%
“…1). The finding that the inoculation technique did not cause any trauma to animals can be explained by the fact that frontal lobectomy is tolerated in both humans [49] and rats [50], as frontal lobes are mainly committed to behavioural and cognitive functions. We decided to use MF1 outbred mice because this strain is well-known for its susceptibility to both intranasal [40,51,52] and intravenous [47] challenge with S. pneumoniae , and because the use of outbred strains is cost-effective.…”
Section: Discussionmentioning
confidence: 99%