2015
DOI: 10.1016/j.ccc.2015.03.007
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Neuromuscular Disorders and Sleep in Critically Ill Patients

Abstract: Synopsis Sleep-disordered breathing (SDB) is a frequent presenting manifestation of neuromuscular disorders and can lead to significant morbidity and mortality. If not promptly recognized and addressed early in the clinical course, SDB can lead to clinical deterioration with respiratory failure. In this article, we review the pathophysiologic basis of SDB in neuromuscular disorders, clinical features encountered in specific neuromuscular diseases, and diagnostic and management strategies for SDB in neuromuscul… Show more

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Cited by 14 publications
(2 citation statements)
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“…Perawat atau dokter seringkali mengalami kesulitan dalam menilai kekuatan otot pada pasien kritis. Pengukuran kekuatan otot dapat dilakukan langsung pada pasien kritis selama perawatan, namun ada pertimbangkan untuk tidak mengganggu peralatan medis yang terpasang pada tubuh pasien (Irfan, Selim, Rabinstein, & Louis, 2015).…”
Section: Pendahuluanunclassified
“…Perawat atau dokter seringkali mengalami kesulitan dalam menilai kekuatan otot pada pasien kritis. Pengukuran kekuatan otot dapat dilakukan langsung pada pasien kritis selama perawatan, namun ada pertimbangkan untuk tidak mengganggu peralatan medis yang terpasang pada tubuh pasien (Irfan, Selim, Rabinstein, & Louis, 2015).…”
Section: Pendahuluanunclassified
“…Upper airway and respiratory muscle weakness are both involved in sleep-related breathing disorder (SRBD) in MDs. A high body mass index (BMI), tongue muscle weakness (especially in DM [46]) as well as craniofacial abnormalities favoring anatomical defects, can predispose patients to upper airways obstruction and OSAS during sleep. During REM (rapid eye movement) sleep and in NREM (non-rapid eye movement) deep sleep, upper airway resistance increases because the tone of skeletal muscles such as pharyngeal dilator falls.…”
Section: Causes Of Hypoxia and Hif-1α Pathway Activation In Mds 21 Respiratory Complications In Muscular Dystrophymentioning
confidence: 99%