Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease

Maddocks, Matthew; Gao, Wei; Higginson, Irene J; Wilcock, Andrew

doi:10.1002/14651858.cd009419.pub2

Cited by 48 publications

(24 citation statements)

References 43 publications

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“…Electrical stimulation has been proved to be very effective in restoring muscle mass and function in denervated muscles (Kern et al, 2004, 2008, 2010; Carraro et al, 2005; Ashley et al, 2007; Maddocks et al, 2013). …”

Section: Discussionmentioning

confidence: 99%

“…ES has been used in clinical settings for rehabilitation purposes, as an alternative therapeutic approach to counteract neuromuscular disability, as well as for muscle strengthening and maintenance of muscle mass in seniors (Maddocks et al, 2013). In addition, there are studies showing that patients with knee osteoarthritis can benefit from the use of ES alone or as an adjunct therapy (Rosemffet et al, 2004; Levine et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Electrical Stimulation Counteracts Muscle Decline in Seniors

Kern

Barberi

Löefler

et al. 2014

Front. Aging Neurosci.

135

144

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The loss in muscle mass coupled with a decrease in specific force and shift in fiber composition are hallmarks of aging. Training and regular exercise attenuate the signs of sarcopenia. However, pathologic conditions limit the ability to perform physical exercise. We addressed whether electrical stimulation (ES) is an alternative intervention to improve muscle recovery and defined the molecular mechanism associated with improvement in muscle structure and function. We analyzed, at functional, structural, and molecular level, the effects of ES training on healthy seniors with normal life style, without routine sport activity. ES was able to improve muscle torque and functional performances of seniors and increased the size of fast muscle fibers. At molecular level, ES induced up-regulation of IGF-1 and modulation of MuRF-1, a muscle-specific atrophy-related gene. ES also induced up-regulation of relevant markers of differentiating satellite cells and of extracellular matrix remodeling, which might guarantee shape and mechanical forces of trained skeletal muscle as well as maintenance of satellite cell function, reducing fibrosis. Our data provide evidence that ES is a safe method to counteract muscle decline associated with aging.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Electrical Stimulation Counteracts Muscle Decline in Seniors

Kern

Barberi

Löefler

et al. 2014

Front. Aging Neurosci.

135

144

View full text Add to dashboard Cite

show abstract

“…Importantly, physical function was strongly associated with worse status for both outcome measures (FACT-G + Pal and POS). The role of rehabilitation is key for patients with progressive illness, as function can be maximised within palliative care planning [32,33]. The worse total scores for Ugandan patients in multivariable analysis may also reflect the referral criteria across countries, in that the Ugandan service may assume care for those with greatest need.…”

Section: Discussionmentioning

confidence: 99%

Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures

Harding

Selman

Ali³

et al. 2014

Health and Quality of Life Outcomes

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BackgroundDespite the high mortality rates of HIV and cancer in sub-Saharan Africa, there are few outcome tools and no comparative data across conditions. This study aimed to measure multidimensional wellbeing among advanced HIV and/or cancer patients in three African countries, and determine the relationship between two validated outcome measures.MethodsCross-sectional self-reported data from palliative care populations in Kenya, Uganda and South Africa using FACIT-G+Pal and POS measures.ResultsAmong 461 participants across all countries, subscale “social and family wellbeing” had highest (best) score. Significant country effect showed lower (worse) scores for Uganda on 3 FACIT G subscales: Physical, Social + family, and functional. In multiple regression, country and functional status accounted for 21% variance in FACIT-Pal. Worsening functional status was associated with poorer POS score. Kenyans had worse POS score, followed by Uganda and South Africa. Matrix of correlational coefficients revealed moderate correlation between the POS and FACIT-Pal core scale (0.60), the FACIT-G and POS (0.64), and FACIT-G + Pal with POS (0.66).ConclusionsThe data reveal best status for family and social wellbeing, which may reflect the sample being from less individualistic societies. The tools appear to measure different constructs of wellbeing in palliative care, and reveal different levels of wellbeing between countries. Those with poorest physical function require greatest palliative and supportive care, and this does not appear to differ according to diagnosis.

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“…Secondly, the relationship between research evidence and usage is a bit more complicated and controversial, with the ambiguity surrounding the evidence being cited by some as a reason why the usage of EPA has been decreasing over the past few decades2 ) . However, this argument ignores the fact that there are now more randomized controlled trials and systematic reviews that have demonstrated treatment effectiveness for patients with a variety of medical conditions such as urinary incontinence34 ) , neck35 ) and knee pain36 ) , muscle weakness37 ) , and spasticity38 ) , among others, which seems to be in direct contradiction to its decreased availability and usage. Thirdly, the association between the other external factors (clinical guidelines, textbooks, workplace protocols, equipment demonstration) and usage may not be as important, since these factors were ranked among the lowest four out of the eight factors.…”

Section: Discussionmentioning

confidence: 99%

Availability, usage, and factors affecting usage of electrophysical agents by physical therapists: a regional cross-sectional survey

2016

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[Purpose] The aim of this study was to investigate the availability, usage, and factors affecting usage of electrophysical agents by physical therapists in Nagano Prefecture, Japan. [Subjects and Methods] Questionnaires were sent to all 1,571 physical therapists working in 245 institutions within Nagano Prefecture. A total of 1,110 questionnaires were returned, out of which 1,099 (70%) questionnaires containing valid responses were analyzed. Frequencies and percentages were calculated for 22 modalities with regards to availability, usage, rate of usage, and confidence level in usage. Factors affecting usage and the relationship between rate of usage and confidence level (Spearman’s rho) were also determined. [Results] The top three responses for the various outcome measures were as follows: (1) hot packs (88%), low frequency stimulators (76%), and ultrasound (68%) for availability; (2) hot packs (72%), ultrasound (61%), and cold packs (59%) for usage; (3) hot packs (75%), cold spray (49%), and ultrasound (44%) for confidence in usage; and (4) equipment availability (80%), past experience (79%), and research evidence (78%) for factors affecting usage. There was a significant positive relationship between confidence and usage for all modalities, except for ultraviolet radiation, iontophoresis, and magnetic field. [Conclusion] Usage was strongly correlated with confidence, with the top three used modalities also being the ones with the highest confidence in usage.

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Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease

Cited by 48 publications

References 43 publications

Electrical Stimulation Counteracts Muscle Decline in Seniors

Electrical Stimulation Counteracts Muscle Decline in Seniors

Wellbeing among sub-Saharan African patients with advanced HIV and/or cancer: an international multicentred comparison study of two outcome measures

Availability, usage, and factors affecting usage of electrophysical agents by physical therapists: a regional cross-sectional survey

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