Neuromuscular joint function in knee osteoarthritis: A systematic review and meta-analysis

Tayfur, Beyza; Charuphongsa, Chedsada; Morrissey, Dylan; Miller, Scott F.

doi:10.1016/j.rehab.2022.101662

Cited by 16 publications

(10 citation statements)

References 72 publications

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“…This appears consistent with what we have learned over the past few years, and the immense ongoing challenges to alleviate the burden of disability at the knee among aging populations. As with earlier studies in this realm [45,46] the prevailing data appear to be in general agreement that there is a risk of prolonged knee joint damage or progressive functional disturbances if one or more of the knee muscles surrounding an osteoarthritic joint are atrophic [21], although this may hard to detect or isolated to a single muscle group [47]. Accordingly, recommendations concerning exercise as a panacea to counter knee osteoarthritis disability prevail widely, but most studies that assess this idea do not account for the nature of any underlying muscle pathology or specific muscle fiber size abnormalities that may have a treatable origin.…”

Section: Discussionsupporting

confidence: 65%

Muscle Atrophy and Knee Osteoarthritis Joint Status: Highlights and their Implications [2017-2023]

Marks¹

2023

Act Scie Ortho

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Osteoarthritis, a disabling disease, commonly believed to originate in the cartilage lining of freely moving joints such as the knee, is increasingly shown to affect and/or be impacted by various muscle deficits surrounding the joint. This brief highlights the current research being published in this respect as far as evidence to support the importance of evaluating and treating any identified muscle atrophy in cases with or vulnerable to one or more manifestations of knee osteoarthritis. To this end, PUBMED, Google Scholar, and PubMed Central indices were selected to identify information specifically pertaining to the topic of muscle atrophy using the key words: Knee Osteoarthritis and Muscle/Muscle Fiber Atrophy. Results show, a reasonable body of current science based evidence supports the view that muscles at the knee joint are important to target in efforts to mitigate knee osteoarthritis in later life. While failing to provide in depth insights into muscle atrophy impacts, it appears treatments directed towards improving muscle structure and function at the knee joint hold promise for mitigating multiple knee osteoarthritis pathogenic disabling processes. Conversely, a failure to identify what components of the muscle system are specifically implicated in the osteoarthritis disease process at the knee joint may be expected to produce more negative or suboptimal clinical outcomes than not. considerations". Genes 11.8 (2020): 854. 57. Singla Ravi., et al. "The course of knee extensor strength after total knee arthroplasty: a systematic review with metaanalysis and -regression". Archives of Orthopaedic and Trauma

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Section: Discussionsupporting

confidence: 65%

Muscle Atrophy and Knee Osteoarthritis Joint Status: Highlights and their Implications [2017-2023]

Marks¹

2023

Act Scie Ortho

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“…Non-pharmacological approaches, such as exercise, weight loss, and healthy diet are strongly recommended in managing KOA 21. Exercise has the benefits of muscle strengthening and hypertrophy, weight management, and potential disease-modifying effects 79–81. Traditional exercise training focuses on improving muscle strength, which is critical to the mobility of KOA patients.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Yijinjing exercise in the treatment of early-stage knee osteoarthritis: a randomized controlled trial protocol

Guo,

Wang,

et al. 2024

BMJ Open

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IntroductionKnee osteoarthritis (KOA) is still a challenging degenerative joint disease with high morbidity and disease burden. Early-stage KOA, the focus of this study, could present a Window of Opportunity to arrest the disease process and reduce the disease burden. Yijinjing exercise is an important part of physical and psychological therapies in Traditional Chinese Exercise and may be an effective treatment. However, there is no clinical efficacy assessment of Yijinjing exercise for patients with early-stage KOA. Therefore, we designed a randomised controlled trial to evaluate the effectiveness of Yijinjing exercise on patients with early-stage KOA.Methods and analysisThis is a parallel-design, two-arm, analyst assessor-blinded, randomised controlled trial. In total, 60 patients with early-stage KOA will be recruited and randomly assigned to the Yijinjing exercise group (n=30) and health education group (n=30) at a ratio of 1:1, receiving 12 weeks of Yijinjing exercise or health education accordingly. The primary outcome will be measured with the Western Ontario and McMaster Universities Osteoarthritis Index, and the secondary outcomes will include the Visual Analogue Scale, Short-Form 36 Item Health Survey Questionnaire, Beck Depression Inventory, Perceived Stress Scale, Berg Balance Scale, and Gait Analysis for a comprehensive assessment. Outcome measures are collected at baseline, at 12 week ending intervention and at the 12 week, 24 week and 48 week ending follow-up. The primay time point will be 12 weeks postintervention. Adverse events will be recorded for safety assessment.Ethics and disseminationThis study has been approved by the ethical application of the Shanghai Municipal Hospital of Traditional Chinese Medicine Ethics Committee (2021SHL-KY-78).Trial registration numberChiCTR2200065178

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“…Since different components of the quadriceps muscles may undergo differing rates or mechanisms of pre-or post-arthritic change, uncovering those most relevant in this regard, and applying target specific treatment approaches accordingly may prove especially helpful for maximizing life quality, the status of the knee muscles in the event surgery is required, plus possibly averting the spread of the disease to other knee and/or distant joint sites. The routine assessment of muscle circumference, muscle fat and tissue content, coupled with an exam of basic reflexive neurological status, measures of gait and lower limb loading using a force plate, plus quadriceps power and endurance in early as well as moderate cases of knee osteoarthritis and that may be especially helpful in securing more precise insights into ant prevailing quadriceps pathology and its optimal rehabilitation where indicated has been discussed [95][96][97][98][99].…”

Section: Discussionmentioning

confidence: 99%

Quadriceps Muscle Mechanics and Knee Osteoarthritis - A 2022 Update

Marks¹

2022

JOSR

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Background: Knee joint osteoarthritis is a highly disabling disease with no distinct cause that persists unabated despite decades of research. Among the various possible causes and factors that influence the progression of the disease other than age and trauma may be various forms of muscle dysfunction, especially among the key knee extensor muscle group known as the quadriceps femoris. Aim: This narrative review strove to examine some pertinent past and recent 2022 research highlights in this respect and to offer possible research recommendations in this regard. Methods: To achieve the review aims, the PUBMED data base and others housing reports aligned with this topic was searched using the key words knee osteoarthritis and quadriceps/knee extensor muscles. Pertinent 2022 and related data were carefully examined and the study researchers’ approaches, conclusions, and recommendations were duly recorded. Results: Many diverse studies within the desired topical theme prevail, rendering it challenging to discern or extract any meaningful trend or conceptuality sound deterministic theory of causation or pathogenic osteoarthritis insights. Even in the realm where multiple publications are available on a single theme, conclusions and design approaches remain inconsistent and of possible moderate quality at best. Conclusion: Efforts to examine and intervene to avert one or more manifestations of quadriceps muscle dysfunction may prove to be highly important in the realm of favorably influencing or minimizing excess osteoarthritis knee joint dysfunction, regardless of whether knee extensor muscle dysfunction is a reactive, rather than a causative factor, but requires a more profound evidence base.

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Neuromuscular joint function in knee osteoarthritis: A systematic review and meta-analysis

Cited by 16 publications

References 72 publications

Muscle Atrophy and Knee Osteoarthritis Joint Status: Highlights and their Implications [2017-2023]

Muscle Atrophy and Knee Osteoarthritis Joint Status: Highlights and their Implications [2017-2023]

Effectiveness of Yijinjing exercise in the treatment of early-stage knee osteoarthritis: a randomized controlled trial protocol

Quadriceps Muscle Mechanics and Knee Osteoarthritis - A 2022 Update

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