Neuronal activity in monkey primary somatosensory cortex is related to expectation of somatosensory and visual go-cues

Liu, Yu; Denton, John M.; Nelson, Randall J.

doi:10.1007/s00221-006-0702-5

Cited by 7 publications

(11 citation statements)

References 55 publications

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“…1(c)-(d). We believe that such strong modulation is related to the role of somatosensory cortex in sensorimotor integration, as discussed in [15]- [16].…”

Section: B Source Localizationmentioning

confidence: 72%

Task-related MEG source localization via discriminant analysis

Zhang

Sudre

et al. 2011

2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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Abstract-To investigate the neural activity corresponding to different cognitive states, it is of great importance to localize the cortical areas that are associated with task-related modulation. In this paper, we propose a novel discriminant pattern source localization (DPSL) method to analyze MEG data. Unlike most traditional source localization methods that aim to find "dominant" sources, DPSL is developed to capture the "differential" sources that distinguish different cognitive states. As will be demonstrated by the experimental results in this paper, the proposed DPSL method offers superior accuracy to identify the spatial locations of task-related sources.

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“…1(c)-(d). We believe that such strong modulation is related to the role of somatosensory cortex in sensorimotor integration, as discussed in [15]- [16].…”

Section: B Source Localizationmentioning

confidence: 72%

Task-related MEG source localization via discriminant analysis

Zhang

Sudre

et al. 2011

2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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show abstract

“…Moreover, we observed that the activity of some SI neurons changed during the IDP when monkeys awaited vibratory or visual stimuli that guided wrist movements (Liu et al 2007). These observations strongly suggested to us that central inputs from other cortical areas may modulate neuronal activity in SI.…”

Section: Discussionmentioning

confidence: 91%

“…Records of wrist position showed that no wrist movements were detected throughout the IDPs and RTPs for correctly performed trials (Liu et al 2007). In the present study, neuronal activity during the early RTPs was examined.…”

Section: Early Rtps Of the Paradigmsmentioning

confidence: 96%

“…Our experimental design did not allow us to investigate specifically the types of fibers that carry the sensory signals from cutaneous or deep tissues. However, the source of vibratory input during the early RTPs might not involve the results of tendon-stretch because recorded profiles showed no changes in hand position (Liu et al 2005(Liu et al , 2007. The angular deflection of the plate that resulted during the vibration was less than 0.06°, which would be too small to cause significant joint movements.…”

Section: Vibration-entrained Si Neurons and Receptive Fieldsmentioning

confidence: 99%

“…In both conditions, however, the reaction times are significantly shorter than during movements initiated by visual go-cues only (Nelson et al 1990;Liu et al 2007). We wondered if the activity of vibration-sensitive SI neurons differs during the two conditions (i.e., VIB and COM trials).…”

Section: Introductionmentioning

confidence: 96%

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Monkey primary somatosensory cortical activity during the early reaction time period differs with cues that guide movements

2008

Self Cite

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Vibration-related neurons in monkey primary somatosensory cortex (SI) discharge rhythmically when vibratory stimuli are presented. It remains unclear how functional information carried by vibratory inputs is coded in rhythmic neuronal activity. In the present study, we compared neuronal activity during wrist movements in response to two sets of cues. In the first, movements were guided by vibratory cue only (VIB trials). In the second, movements were guided by simultaneous presentation of both vibratory and visual cues (COM trials). SI neurons were recorded extracellularly during both wrist extensions and flexions. Neuronal activity during the instructed delay period (IDP) and the early reaction time period (RTP) were analyzed. A total of 96 cases from 48 neurons (each neuron contributed two cases, one each for extension and flexion) showed significant vibration entrainment during the early RTPs, as determined by circular statistics (Rayleigh test). Of these, 50 cases had cutaneous (CUTA) and 46 had deep (DEEP) receptive fields. The CUTA neurons showed lower firing rates during the IDPs and greater firing rate changes during the early RTPs when compared with the DEEP neurons. The CUTA neurons also demonstrated decreases in activity entrainment during VIB trials when compared with COM trials. For the DEEP neurons, the difference of entrainment between VIB and COM trials was not statistically significant. The results suggest that somatic vibratory input is coded by both the firing rate and the activity entrainment of the CUTA neurons in SI. The results also suggest that when vibratory inputs are required for successful task completion, the activity of the CUTA neurons increases but the entrainment degrades. The DEEP neurons may be tuned before movement initiation for processing information encoded by proprioceptive afferents.

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Optical imaging of digit topography in individual awake and anesthetized squirrel monkeys

2009

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Topographic maps and columnar structures are fundamental to cortical sensory information processing. Most of the knowledge about detailed topographic maps and columnar structure comes mainly from experiments conducted on anesthetized animals. Towards the goal of evaluating whether topographic maps change with respect to behavioral demands, we used intrinsic signal optical imaging in alert monkeys to examine the spatial specificity of cortical topographic representation. Specifically, the somatotopies of neighboring distal finger pad representation in areas 3b and 1 were examined in the same awake and anesthetized squirrel monkey. In comparison to the anesthetized animal, we found larger cortical activation sizes in the alert animal in area 3b, where activation widths were found to overlap with even non-adjacent digits. This may suggest that in the alert animal, there is less inhibition across the somatotopic map within area 3b.

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Neuronal activity in monkey primary somatosensory cortex is related to expectation of somatosensory and visual go-cues

Cited by 7 publications

References 55 publications

Task-related MEG source localization via discriminant analysis

Task-related MEG source localization via discriminant analysis

Monkey primary somatosensory cortical activity during the early reaction time period differs with cues that guide movements

Optical imaging of digit topography in individual awake and anesthetized squirrel monkeys

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