Neuropathic Manifestations in Infants and Children as a Result of Anaphylactic Reaction to Foods Contained in Their Dietary

Abstract

The close association of the exudative and neuropathic diatheses suggests a causal relationship. The frequent anaphylactic nature of the former 1 would seem to point toward a similar cause in the latter.It is my purpose in this paper to discuss certain nervous manifestations in infants and children from the standpoint of anaphylactic cause.It is hardly necessary to call attention to the frequent occurrence of the exudative and neuropathic diatheses in the same individual. All observers recognize the common association. However, it seems to have been generally held that this relationship is nothing more than accidental. Czerny considered it so.2 He felt that the almost universal presence of the neuropathic diathesis in one or both parents of children with the exudative diathesis led, as a natural result, to the neurotic child. The degree to which the infant was affected by this nervous environment determined, to a certain extent, the obstinacy and severity of the exudative manifestations. Pfaundler 3 stated that the sneezing in coryza, pertussoid in bronchitis, asthma in bronchiolitis, severe colic in enteritis, etc., were dependent, to a certain degree, on the coexistence of a neuropathic diathesis along with the exudative diathesis.This common association, together with the fact that frequently in the same individual the symptoms of one, and again the symptoms of the other diathesis, will seem to predominate, led me to the opinion that not infrequently the symptoms of both conditions might be due to the same underlying factor. Inquiry revealed the fact that often nervous patients have a history, either personal or familial, of exudative dis¬ turbances, and the frequent anaphylactic basis for the exudative phenomena suggested that the nervous symptoms might also be due to this cause. Therefore, this investigation was undertaken to see if this might not be the case clinically.The cases presented are of three types ; first, the type in which the symptoms of both diatheses were plainly present; second, the type in

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