Neuropathic Orofacial Pain

Neuralgia induzida por cavitação osteonecrótica

“…Neuromodulators significantly improve pain in the beginning, and there may be pain latency periods. There are cases where pain returns without apparent reasons [25][26][27][28][29][32][33][34][35] . Glossopharyngeal neuralgia is similar to trigeminal neuralgia being differentiated by the anatomic site.…”

“…Studies 3,19 have proposed the following diagnostic criteria: pain in the alveolar bone in regions innervated by the trigeminal nerve and temporary pain relief when the region is submitted to anesthetic block. NICO also interferes with quality of life and may be easily mistaken for other neuropathic and / or deep somatic musculoskeletal and visceral diseases 4,8,9,[25][26][27][28][29] .…”

Neuropathic pain after dental treatment

“…[9] It should be stated that studies are not unanimous on this issue. [19] Besides these characteristics, aching pain does not preclude the possibility of a neuropathic basis for the patient's pain.…”

“…The episodic neuropathic pain presents as periods of total remission of symptoms whereas the continuous neuropathic pain is an ongoing unremitting pain condition. [8,9] The true prevalence of neuropathic pain is not known. It has been estimated that 1-1.5% of the general population is affected.…”

“…A neuroma is a tangled mass of nervous tissue in conjunction with proliferated Schwann cells. [9,14,15] Ephaptic transmission Abnormal connections may occur between or among two or more adjacent demyelinated or unmyelinated axons of damaged nerve. [14,15] Central sprouting A-beta afferent fibers sprout into more superficial layers in the dorsal horn making synaptic contacts with nociceptive neurons.…”