Neuropathic Pain, Depression, and Cardiovascular Disease: A National Multicenter Study

Cragg, Jacquelyn J.; Noonan, Vanessa K.; Noreau, Luc; Borisoff, Jaimie; Kramer, J. K. G.

doi:10.1159/000377726

Cited by 25 publications

(20 citation statements)

References 38 publications

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“…This suggests that the prevalence of neuropathic pain in our investigation was almost 16%. Recent reports show the prevalence of neuropathic pain ranges from 7% to 29.4% [ 13 , 21 – 26 ]. Thus, there was an average prevalence of neuropathic pain in our investigation compared to these studies in developed countries.…”

Section: Discussionmentioning

confidence: 99%

Pain Prevalence and Pain Management in a Chinese Hospital

Hong

Liu

et al. 2018

Med Sci Monit

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BackgroundPain prevalence has been investigation in many developed countries, but integrated information about pain prevalence in Chinese hospitals is lacking. To achieve better pain treatment of hospitalized patients, pain management needs to be investigated. The present descriptive and cross-sectional study was performed to demonstrate the prevalence of pain by comparison with the 4 traditional vital signs, and to investigate pain management in a Chinese teaching hospital.Material/MethodsStructured and systematic interviews were undertaken by independent researchers. During a patient’s hospitalization, the prevalence of pain and the 4 vital signs were recorded. Then, the catalog, severity, causes, duration of pain, and pain management were assessed.ResultsWe found: (1) 63.36% of patients (3248 in total) suffered from pain while in hospital, which was 1.8~2.8 times higher than the prevalence of abnormality of the 4 vital signs. (2) 76% of patients had moderate pain and 21.98% had severe pain. (3) Pain intensity differed among patients with different diseases, but did not differ by demographic factors. (4) Acute and chronic pain were present in 68% and 26% of patients, respectively. In addition, 16% of the patients had neuropathic pain. (5) More than half of the patients with pain refused to receive pain-relief medication because they worried about addiction to opioids and the adverse effects of analgesics. (6) Most medical staff properly understood the 3 ladder analgesics.ConclusionsThe prevalence of pain is higher than the abnormality of the 4 traditional vital signs in a Chinese hospital. Although pain management has broadly improved, more patient education is necessary.

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Section: Discussionmentioning

confidence: 99%

Pain Prevalence and Pain Management in a Chinese Hospital

Hong

Liu

et al. 2018

Med Sci Monit

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“…People with SCI suffer substantial muscle atrophy 4 and altered body composition, 5 which likely contribute to their increased susceptibility to secondary complications. 6,7 Although considerable evidence has been compiled in animal models, we focus on relevant human studies. The early work in the late 1970s reported significant myofiber atrophy and a predominantly fast composition as compared to able-bodied counterparts.…”

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confidence: 99%

Neuromuscular Electrical Stimulation–Induced Resistance Training After SCI: A Review of the Dudley Protocol

Bickel

Yarar‐Fisher

Mahoney

et al. 2015

Topics in Spinal Cord Injury Rehabilitation

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Background: Neuromuscular electrical stimulation (NMES), often referred to as functional electrical stimulation (FES), has been used to activate paralyzed skeletal muscle in people with spinal cord injury (SCI). The goal of NMES has been to reverse some of the dramatic losses in skeletal muscle mass, to stimulate functional improvements in people with incomplete paralysis, and to produce some of the health benefits associated with exercise. Objective: The purpose of this brief review is to describe a quantifiable resistance training form of NMES developed by Gary A. Dudley. Methods: People with motor complete SCI were first tested to confirm that an NMES-induced muscle contraction of the quadriceps muscle could be achieved. The contraction stimulus consisted of biphasic pulses at 35 Hz performed with increasing current up to what was needed to produce full knee extension. Four sets of 10 knee extensions were elicited, if possible. Training occurred biweekly for 3 to 6 months, with ankle weights being increased up to an added weight of 9.1 kg if the 40 repetitions could be performed successfully for 2 sessions. Results: Many participants have performed this protocol without adverse events, and all participants showed progression in the number of repetitions and/or the amount of weight lifted. Large increases in muscle mass occur, averaging 30% to 40%. Additional physiological adaptations to stimulated muscle have also been reported. Conclusions: These results demonstrate that the affected skeletal muscle after SCI responds robustly to progressive resistance training many years after injury. Future work with NMES should determine whether gains in lean mass translate to improved health, function, and quality of life.

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“…There are about 17,000 new cases to happen from 280,000 patients with SCI in the United States alone every year (Spinal Cord Injury 2016 Facts andFigures at a Glance , 2016). Among patients with spinal cord injury, 80% of individuals experienced a severe sensory deficit-neuropathic pain (Cragg et al, 2015;Finnerup et al, 2014;Siddall and Loeser, 2001;Siddall et al, 2003). Currently, stabilizing the cord and restoring homeostasis immediately following injury for patients with SCI was the most acute treatments (Chang et al, 2013;Edgerton and Harkema, 2011;Khurana and Garg, 2014).…”

Section: Introductionmentioning

confidence: 99%