Neuroprotective Spice Herbs for Neuroinflammation and Neurodegeneration Diseases

Abstract

Traditional medicine has received more attention in recent years. Numerous plants have been employed in medicine to treat neurological disorders like AD and other memory-related problems. Traditional uses for dietary, spice, and food additive medicinal purposes included the use of, Nigella sativa, Crocus sativus, Ferula assafoetida, Coriandrum sativum, Zataria multiflora, Thymus vulgaris Cats Claw, and Carotenoids, monoterpenes, and polyphenol chemicals, which are the main ingredients in these plants, improved neurological processes. These healing plants improved antioxidant production, reduced oxidative stress, and prevented the neurological system's acetylcholinesterase enzyme from working. Reduced production of proinflammatory cytokines such IL-6, TNF-an ,IL-1b, NF-Kβ, Bax Protein, Bcl-2,Caspase-3 and total nitrite is another way that plants are neuroprotective. As a result, the effects of the aforementioned medications and their active ingredients improved neurodegenerative diseases, indicating their therapeutic promise in diseases like AD and depression that are linked to neuro-inflammation and neurotransmitter deficit.