Neuropsychiatric symptoms and associated caregiver stress in geriatric patients with Parkinson’s disease

doi:10.3823/352

Cited by 2 publications

(2 citation statements)

References 39 publications

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“…These findings confirm the importance and severity of persons’ neuropsychiatric symptoms and emotional distress that is produced in early-stage and middle-stage family caregivers. It has already been suggested that neuropsychiatric symptoms amongst persons with AD have a negative impact on both the caregivers’ mental health [48] and the expenditure of healthcare systems [49]. It is also known that family caregivers’ burden can worsen the person-caregiver relationship, which can in turn increase the severity of persons’ neuropsychiatric symptoms [10].…”

Section: Discussionmentioning

confidence: 99%

Predictor Factors of Perceived Health in Family Caregivers of People Diagnosed with Mild or Moderate Alzheimer’s Disease

Fernández

Hernández‐Padilla

Ortiz‐Amo

et al. 2019

IJERPH

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Caring for a person diagnosed with Alzheimer’s disease has a negative impact on family caregivers’ psychological health. This study examined the factors related to ‘perceived health’ and ‘presence of new-onset mental health problems’ in family caregivers of people diagnosed with mild and moderate Alzheimer’s disease. A cross-sectional observational study carried out in Almeria’s Healthcare District (Spain). A total of 255 family caregivers (42.4% cared for people with mild Alzheimer’s disease and 57.6% cared for people with moderate Alzheimer’s disease) participated in the study from January to December 2015. Mainly, caregivers were women (81.5% in the mild Alzheimer’s disease group and 88.4% in the moderate Alzheimer’s disease group), and their average age was 56.54 years (standard deviation (SD) = 13.13) and 54.47 years (SD = 11.71), respectively. Around 47% of the caregivers had been caring for the person with Alzheimer’s between two and five years. The Goldberg General Health Questionnaire was used to measure perceived health and the presence of new-onset mental health problems. An exploratory descriptive analysis and a multivariate logistic regression analysis were conducted. For caregivers of people with mild Alzheimer’s disease, ‘perceived health’ was related to ‘perceived social support’ (r = −0.21; p = 0.028), ‘person’s level of dependency’ (r = −0.24, p = 0.05), ‘severity of the person’s neuropsychiatric symptoms’ (r = 0.22; p = 0.05), and ‘caregiver’s emotional distress in response to the person’s neuropsychiatric symptoms’ (r = 0.22; p = 0.05). For caregivers of people with moderate Alzheimer’s disease, ‘perceived health’ was related to ‘perceived social support’ (r = −0.31; p ˂ 0.01), ‘presence of neuropsychiatric symptoms’ (r = 0.27, p = 0.01), ‘severity of the person’s neuropsychiatric symptoms’ (r = 0.32, p = 0.01) and ‘caregiver’s emotional distress in response to the person’s neuropsychiatric symptoms’ (r = 0.029; p = 0.01). The presence of new-onset mental health problems was detected in 46.3% (n = 50) of caregivers of people with mild Alzheimer’s and 61.9% (n = 91) of caregivers of people with moderate Alzheimer’s. When people are diagnosed with mild Alzheimer’s disease, intervention programs for caregivers should aim to regulate emotions and promote positive coping strategies. When people are diagnosed with moderate Alzheimer’s disease, intervention programs for caregivers must allow them to adapt to caregiving demands that arise with the progression of Alzheimer’s disease.

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Section: Discussionmentioning

confidence: 99%

Predictor Factors of Perceived Health in Family Caregivers of People Diagnosed with Mild or Moderate Alzheimer’s Disease

Fernández

Hernández‐Padilla

Ortiz‐Amo

et al. 2019

IJERPH

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“…The Park apathy subtype has been associated with more severe motor symptoms, confirmed in observational studies [ 3 ]. Apathetic patients score higher on the UPDRS motor scale than their non-apathetic peers, excluding confounding factors such as disease duration or age [ 8 , 9 , 22 , 130 , 131 ]. This difference is already manifest at diagnosis, before the introduction of DRT [ 4 , 7 , 8 , 22 , 37 ].…”

Section: Park Apathymentioning

confidence: 99%

Apathy in Parkinson’s Disease: Defining the Park Apathy Subtype

2022

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Apathy is a neurobehavioural symptom affecting Parkinson’s disease patients of all disease stages. Apathy seems to be associated with a specific underlying non-motor disease subtype and reflects dysfunction of separate neural networks with distinct neurotransmitter systems. Due to the complicated neuropsychiatric aetiology of apathy, clinical assessment of this invalidating non-motor symptom remains challenging. We aim to summarize the current findings on apathy in Parkinson’s disease and highlight knowledge gaps. We will discuss the prevalence rates across the different disease stages and suggest screening tools for clinically relevant apathetic symptoms. We will approach the fundamental knowledge on the neural networks implicated in apathy in a practical manner and formulate recommendations on patient-tailored treatment. We will discuss the Park apathy phenotype in detail, shedding light on different clinical manifestations and implications for prognosis. With this review, we strive to distil the vast available theoretical knowledge into a clinical and patient-oriented perspective.

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Neuropsychiatric symptoms and associated caregiver stress in geriatric patients with Parkinson’s disease

Cited by 2 publications

References 39 publications

Predictor Factors of Perceived Health in Family Caregivers of People Diagnosed with Mild or Moderate Alzheimer’s Disease

Predictor Factors of Perceived Health in Family Caregivers of People Diagnosed with Mild or Moderate Alzheimer’s Disease

Apathy in Parkinson’s Disease: Defining the Park Apathy Subtype

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